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Study · Measured the body's own peptide · 2010

4 results

Vitamin D status and antimicrobial peptide cathelicidin (LL-37) concentrations in patients with active pulmonary tuberculosis.

Yamshchikov AV, Kurbatova EV, Kumari M, Blumberg HM, Ziegler TR, Ray SM, Tangpricha V

The American journal of clinical nutrition7 Jul 2010Cited by 67 (Europe PMC)

PMID20610636 (opens in a new tab)PMCIDPMC2921537 (opens in a new tab)DOI10.3945/ajcn.2010.29411 (opens in a new tab)PepBankPUB-20610636
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patients with culture-confirmed pulmonary tuberculosis, the mean baseline serum LL‑37 concentration was 49.5 ng/mL.

    In plain wordsIn people with active lung tuberculosis, the body's own LL‑37 in blood averaged 49.5 ng/mL.

    Peptide
    LL-37
    Outcome
    Not applicableBaseline serum LL-37 concentration
    Study

    n = 95

    Outcome group
    Infection and antimicrobial activity · Infection

    Measurements

    Mean baseline serum LL-37
    49.5 ng/mL
    patients with active tuberculosis

    Source sentences

    Summary
    The mean ( plusmn SD) baseline LL-37 concentration was 49.5 plusmn 23.8 ng/mL.
    1 context sentence
    Summary · context
    We measured 25-hydroxyvitamin D [25(OH)D] and LL-37 concentrations in 95 serum specimens from patients with culture-confirmed pulmonary tuberculosis and correlated these concentrations to clinical and demographic variables.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patients with pulmonary tuberculosis, higher serum LL‑37 concentrations correlated with acid fast bacilli sputum smear positivity.

    In plain wordsIn people with lung tuberculosis, higher body's own LL‑37 in blood was linked to a positive sputum smear test.

    Peptide
    LL-37
    Outcome
    Not applicableSerum LL-37 and sputum smear positivity
    Study

    n = 95

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Higher LL-37 concentrations correlated with acid fast bacilli sputum smear positivity and weight gt 10% below ideal body weight.
    1 context sentence
    Summary · context
    We measured 25-hydroxyvitamin D [25(OH)D] and LL-37 concentrations in 95 serum specimens from patients with culture-confirmed pulmonary tuberculosis and correlated these concentrations to clinical and demographic variables.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In patients with pulmonary tuberculosis, higher serum LL‑37 concentrations correlated with weight more than 10% below ideal body weight.

    In plain wordsIn people with lung tuberculosis, higher body's own LL‑37 in blood was linked to being well below ideal body weight.

    Peptide
    LL-37
    Outcome
    Not applicableSerum LL-37 and low body weight
    Study

    n = 95

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Higher LL-37 concentrations correlated with acid fast bacilli sputum smear positivity and weight gt 10% below ideal body weight.
    1 context sentence
    Summary · context
    We measured 25-hydroxyvitamin D [25(OH)D] and LL-37 concentrations in 95 serum specimens from patients with culture-confirmed pulmonary tuberculosis and correlated these concentrations to clinical and demographic variables.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    In patients with pulmonary tuberculosis, serum vitamin D status did not correlate with serum LL‑37 concentrations.

    In plain wordsIn people with lung tuberculosis, vitamin D status in blood was not linked to the body's own LL‑37 level.

    Peptide
    LL-37
    Outcome
    No significant changeSerum LL-37 and vitamin D status
    Study

    n = 95

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Serum vitamin D status of the study subjects did not correlate with serum LL-37 concentrations.
    1 context sentence
    Summary · context
    We measured 25-hydroxyvitamin D [25(OH)D] and LL-37 concentrations in 95 serum specimens from patients with culture-confirmed pulmonary tuberculosis and correlated these concentrations to clinical and demographic variables.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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