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Study · Animal study (in vivo) · rat · 2011

2 results

Continuous antagonism of the ghrelin receptor results in early induction of salt-sensitive hypertension.

Sato T, Nakashima Y, Nakamura Y, Ida T, Kojima M

Journal of molecular neuroscience : MN2 Jul 2010Cited by 14 (Europe PMC)

PMID20596792 (opens in a new tab)DOI10.1007/s12031-010-9414-1 (opens in a new tab)PepBankPUB-20596792
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Dahl-Iwai salt-sensitive rats, continuous GHRP‑6 administration did not change blood pressure.

    In plain wordsIn rats with salt-sensitive hypertension, continuous GHRP‑6 did not change blood pressure.

    Peptide
    GHRP-6
    Outcome
    No significant changeBlood pressure
    Study

    ratn: not reported in source

    Dahl-Iwai salt-sensitive rats with salt-sensitive hypertension
    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    Dose not stated · mini-osmotic pump · 2 weeksAs given in this study (rat).

    Source sentences

    Summary
    Continuous administration of a ghrelin receptor agonist, growth hormone releasing peptide-6 (GHRP-6), for 2 weeks by mini-osmotic pump did not change blood pressure values although the cumulative food intake recovered.
    1 context sentence
    Summary · context
    We examined the longitudinal effect of ghrelin on vasoregulation using Dahl-Iwai salt-sensitive rats.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In Dahl-Iwai salt-sensitive rats, cumulative food intake recovered during continuous GHRP‑6 administration.

    In plain wordsIn rats with salt-sensitive hypertension, food intake recovered during continuous GHRP‑6 administration.

    Peptide
    GHRP-6
    Outcome
    IncreaseCumulative food intake
    Study

    ratn: not reported in source

    Dahl-Iwai salt-sensitive rats with salt-sensitive hypertension
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    Dose not stated · mini-osmotic pump · 2 weeksAs given in this study (rat).

    Source sentences

    Summary
    Continuous administration of a ghrelin receptor agonist, growth hormone releasing peptide-6 (GHRP-6), for 2 weeks by mini-osmotic pump did not change blood pressure values although the cumulative food intake recovered.
    1 context sentence
    Summary · context
    We examined the longitudinal effect of ghrelin on vasoregulation using Dahl-Iwai salt-sensitive rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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