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Study · Animal study (in vivo) · rat · 2010

3 results

[Changes in duodenal lymphoid structures in rats with various behavioral activity, caused by delta sleep-inducing peptide and following acute emotional stress].

Ivanova EA, Koplik EV

Morfologiia (Saint Petersburg, Russia)1 Jan 2010

PMID20572393 (opens in a new tab)PepBankPUB-20572393
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Wistar rats of all experimental groups, intraperitoneal DSIP reduced eosinophil number.

    In plain wordsIn rats, DSIP injections reduced the number of eosinophils in the gut lining.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseEosinophil number in duodenal lymphoid structures
    Study

    ratn = 42

    duodenal lymphoid structures, open field behavior groups
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Intraperitoneal injection of DSIP resulted in a reduction of eosinophil number in rats of all the experimental groups.
    1 context sentence
    Summary · context
    Studies were conducted on 42 male Wistar rats, which were previously assessed in an "open field" test.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In behaviourally active control rats, DSIP injection increased small and medium lymphocyte numbers, more than in passive rats.

    In plain wordsIn active rats, DSIP injections raised small and medium lymphocyte numbers in the gut lining, more than in passive rats.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseSmall and medium lymphocyte numbers in active control rats
    Study

    ratn: not reported in source

    duodenal lymphoid structures, open field behavior groups
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    After DSIP injection to the active rats of the control group, the increase in small and medium lymphocyte numbers was detected that was more expressed than in the passive rats.
    1 context sentence
    Summary · context
    Studies were conducted on 42 male Wistar rats, which were previously assessed in an "open field" test.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In behaviourally passive rats, stress exposure and DSIP injection together increased plasma cell number in all duodenal mucosa structures studied.

    In plain wordsIn passive rats, stress plus a DSIP injection together raised plasma cell numbers in the gut lining.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreasePlasma cell number in passive rats after stress and DSIP
    Study

    ratn: not reported in source

    duodenal lymphoid structures, open field behavior groups
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    In the group of passive rats, stress exposure and DSIP injection resulted in the increase of plasma cell number in all the duodenal mucosa structures studied.
    1 context sentence
    Summary · context
    Studies were conducted on 42 male Wistar rats, which were previously assessed in an "open field" test.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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