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Study · Randomized controlled trial · 2010

3 results

The neuropeptide oxytocin regulates parochial altruism in intergroup conflict among humans.

De Dreu CK, Greer LL, Handgraaf MJ, Shalvi S, Van Kleef GA, Baas M, Ten Velden FS, Van Dijk E, Feith SW

Science (New York, N.Y.)1 Jun 2010Cited by 582 (Europe PMC)

PMID20538951 (opens in a new tab)DOI10.1126/science.1189047 (opens in a new tab)PepBankPUB-20538951
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In male participants, oxytocin promoted in-group trust and cooperation compared with placebo.

    In plain wordsIn men, oxytocin increased trust and cooperation toward their own group more than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseIn-group trust and cooperation
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    it promoted in-group trust and cooperation, and defensive, but not offensive, aggression toward competing out-groups.
    1 context sentence
    Summary · context
    In three experiments using double-blind placebo-controlled designs, male participants self-administered oxytocin or placebo and made decisions with financial consequences to themselves, their in-group, and a competing out-group.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In male participants, oxytocin promoted defensive aggression toward competing out-groups compared with placebo.

    In plain wordsIn men, oxytocin increased defensive aggression toward a competing group more than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseDefensive aggression toward out-groups
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and defensive, but not offensive, aggression toward competing out-groups.
    1 context sentence
    Summary · context
    In three experiments using double-blind placebo-controlled designs, male participants self-administered oxytocin or placebo and made decisions with financial consequences to themselves, their in-group, and a competing out-group.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In male participants, oxytocin did not promote offensive aggression toward competing out-groups.

    In plain wordsIn men, oxytocin did not increase offensive aggression toward a competing group.

    Peptide
    Oxytocin
    Outcome
    No significant changeOffensive aggression toward out-groups
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and defensive, but not offensive, aggression toward competing out-groups.
    1 context sentence
    Summary · context
    In three experiments using double-blind placebo-controlled designs, male participants self-administered oxytocin or placebo and made decisions with financial consequences to themselves, their in-group, and a competing out-group.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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