[Effect of preparations melatonin and epitalon on the age-related dynamics of thyrotrophic activity of the hypophysis and thyroid gland function in different light regimes].

Vinogradova IA

Advances in gerontology = Uspekhi gerontologii1 Jan 2009Cited by 3 (Europe PMC)

PMID20405731PepBankPUB-20405731

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Epitalon.

01AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome
In rats under different light regimes, age changes of hormone levels appeared later in animals that received melatonin and epitalon than in control animals.
In plain wordsIn rats, age-related hormone changes appeared later in animals given melatonin and epitalon than in controls.
Peptide
Epitalon
Outcome
DecreaseAge-related changes of thyroid hormone levels
Study
ratn: not reported in source
Rats under different light regimes
Outcome group
Thyroid function · Endocrine and hormones
Source sentences
Summary
The age changes of the level of hormones appeared later in rats who received medication, in comparison with the control sets of animals.
1 context sentence(design, population, supporting numbers)
Summary · context
The influence of different light regimes (standard lightning--12 hours light/ 12 hours darkness; natural light regime of the North-West of Russia; constant darkness and constant lightning), melatonin and epitalon on the thyrotrophic activity of hypophysis and on the function of thyroid gland was studied.
In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.
Report a problemFND-2040573101
02AnimalNot a test of Epitalon aloneAnimal study (in vivo)Efficacy outcome
In rats under the natural lighting of Karelia, melatonin and epitalon smoothened the seasonal variations of thyroid hormone levels in blood.
In plain wordsIn rats under natural northern light, melatonin and epitalon reduced the seasonal swings in thyroid hormone levels.
Peptide
Epitalon
Outcome
DecreaseSeasonal variation of thyroid hormones in Karelia lighting
Study
ratn: not reported in source
Rats under different light regimes
Outcome group
Thyroid function · Endocrine and hormones
Source sentences
Summary
The use of melatonin and epitalon smoothened the seasonal variations of the level of thyroidal hormones in blood in the lightning conditions of Karelia.
1 context sentence(design, population, supporting numbers)
Summary · context
The influence of different light regimes (standard lightning--12 hours light/ 12 hours darkness; natural light regime of the North-West of Russia; constant darkness and constant lightning), melatonin and epitalon on the thyrotrophic activity of hypophysis and on the function of thyroid gland was studied.
In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.
Report a problemFND-2040573102

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
12 Oct 2026, 17:28 UTC
Study results updated
Version 1
9 Oct 2026, 02:47 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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