Skip to content

Study · Not a test of the peptide alone · 2010

2 results

[Purification of recombinant proteins with an example of tumor necrosis factor thymosin-alpha1].

Fedorov TV, Korobov VI, Nazarov VG, Smolkina AE, Shmelev VA

Prikladnaia biokhimiia i mikrobiologiia1 Mar 2010

PMID20391771 (opens in a new tab)DOI10.1134/s0003683810020171 (opens in a new tab)PepBankPUB-20391771
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cells)Activity measurement

    A purified hybrid protein of cancer necrosis factor and thymosin-alpha1 (CNF-T) had high cytotoxic activity against mouse L-929 adenocarcinoma cells in vitro.

    In plain wordsIn lab tests, a purified fusion protein that includes thymosin-alpha1 was highly toxic to mouse cancer cells.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableCytotoxic activity of purified CNF-T
    Study

    mousen: not reported in source

    L-929 mouse adenocarcinoma cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    The method allows the isolation of electrophoretically homogeneous CNF-T containing no DDS-Na and having high cytotoxic activity against cancer cells of mouse adenocarcinome L-929.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    Purification of the hybrid protein CNF-T from E. coli reached a yield of 80% relative to its content in biomass and 30% relative to the total protein.

    In plain wordsIn lab tests, a purification method recovered most of a fusion protein that includes thymosin-alpha1 from bacteria.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicablePurification yield of CNF-T
    Study

    n: not reported in source

    Escherichia coli SG200-50 recombinant production
    Outcome group
    Synthesis and manufacturing · Pharmacology

    Measurements

    Yield
    80%
    relative to content in biomass
    Yield
    30%
    relative to total protein

    Source sentences

    Summary
    The yield of CNF-T achieved 80% relative its content in biomass and 30% relative the total protein.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.