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Study · Animal study (in vivo) · mongolian jird · 2010

5 results

[Neuroprotective effect of cerebrocurin in a model of acute cerebral stroke].

Belenichev IF, Pavlov SV, Dunaev VV

Eksperimental'naia i klinicheskaia farmakologiia1 Feb 2010Cited by 1 (Europe PMC)

PMID20369593 (opens in a new tab)PepBankPUB-20369593
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In Mongolian jirds with acute cerebral stroke, cerebrolysin reduced mitochondrial dysfunction on the 4th day.

    In plain wordsIn Mongolian jirds with stroke, cerebrolysin reduced mitochondrial dysfunction.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseMitochondrial dysfunction
    Study

    Mongolian jirdn: not reported in source

    Acute cerebral stroke
    Outcome group
    Mitochondrial function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day
  2. 02AnimalAnimal study (in vivo)Mechanism

    In Mongolian jirds with acute cerebral stroke, cerebrolysin inhibited mitochondrial permeability transition pore opening.

    In plain wordsIn Mongolian jirds with stroke, cerebrolysin reduced the opening of mitochondrial permeability pores.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseMitochondrial permeability transition pore opening
    Study

    Mongolian jirdn: not reported in source

    Acute cerebral stroke
    Outcome group
    Mitochondrial function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    which was manifested by their ability to inhibit the mitochondrial permeability transition pore opening
    1 context sentence
    Summary · context
    Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day
  3. 03AnimalAnimal study (in vivo)Mechanism

    In Mongolian jirds with acute cerebral stroke, cerebrolysin normalized energy metabolism.

    In plain wordsIn Mongolian jirds with stroke, cerebrolysin normalized energy metabolism.

    Peptide
    Cerebrolysin
    Outcome
    Direction not reportedEnergy metabolism
    Study

    Mongolian jirdn: not reported in source

    Acute cerebral stroke
    Outcome group
    Mitochondrial function · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    which was manifested by their ability to inhibit the mitochondrial permeability transition pore opening, normalize the energy metabolism
    1 context sentence
    Summary · context
    Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day
  4. 04AnimalAnimal study (in vivo)Mechanism

    In Mongolian jirds with acute cerebral stroke, cerebrolysin enhanced c-fos gene expression.

    In plain wordsIn Mongolian jirds with stroke, cerebrolysin increased c-fos gene expression.

    Peptide
    Cerebrolysin
    Outcome
    Increasec-fos gene expression
    Study

    Mongolian jirdn: not reported in source

    Acute cerebral stroke
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    which was manifested by their ability to inhibit the mitochondrial permeability transition pore opening, normalize the energy metabolism, and enhance c-fos gene expression.
    1 context sentence
    Summary · context
    Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In Mongolian jirds with acute cerebral stroke, cerebrolysin's effects were statistically weaker than cerebrocurin's across the assessed characteristics.

    In plain wordsIn Mongolian jirds with stroke, cerebrolysin had weaker effects than cerebrocurin across the assessed characteristics.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseOverall effect versus cerebrocurin
    Study

    Mongolian jirdn: not reported in source

    Acute cerebral stroke
    Comparator
    Cerebrocurin
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    With respect to all characteristics under consideration, the effect of cerebrocurin exceeded with statistical confidence that of cerebrolysin.
    1 context sentence
    Summary · context
    Chronic administration of cerebrocurin and cerebrolysin to Mongolian jirds with acute cerebral stroke model led to a decrease in the mitochondrial dysfunction on the 4th day

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

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