In diabetic rats, GHRP‑6 did not improve hyperglycemia compared with saline treatment.
In plain wordsIn rats with diabetes, GHRP‑6 did not improve high blood sugar compared with saline.
- Peptide
- GHRP-6
- Outcome
- No significant changeHyperglycemia
- Study
ratn: not reported in source
streptozotocin-induced diabetes- Comparator
- saline-treated diabetic rats
- Outcome group
- Glycemic control · Metabolic and weight
- Studied dose
- Dose not stated · 8 wkAs given in this study (rat).
Source sentences
Insulin, but not GHRP-6, improved these parameters (P < 0.001 for all), as well as the diabetes-induced increase in hypothalamic mRNA levels of neuropeptide Y and agouti-related peptide and decrease in proopiomelanocortin.
2 context sentences(design, population, supporting numbers)
Rats receiving saline suffered hyperglycemia, hyperphagia, polydipsia, and weight loss.
Streptozotocin-induced diabetic rats received saline, GHRP-6, insulin, or insulin plus GHRP-6 once daily for 8 wk.