In cultured sea bass liver fragments, MTII, a sea bass MC5R agonist, stimulated lipolysis, measured as free fatty acid release.
In plain wordsIn lab tests on sea bass liver tissue, MTII increased the release of fatty acids.
- Peptide
- Melanotan II
- Outcome
- IncreaseHepatic lipolysis (free fatty acid release) in liver fragments
- Study
sea bassn: not reported in source
ex vivo, cultured liver fragments- Outcome group
- Liver fat and liver function · Liver
- Studied dose
- Dose not stated · added to culture mediumAs given in this study (sea bass).
Source sentences
MTII, a sbMC5R agonist, stimulated hepatic lipolysis in vitro, measured as free fatty acid release into the culture medium after melanocortin agonist exposure of liver fragments, suggesting that MC5R is involved in the regulation of hepatic lipid metabolism.