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Study · Non-randomized trial · n = 10 · 2010

10 results

GH-releasing peptide-2 does not stimulate arginine vasopressin secretion in healthy men.

Kamoi K, Minagawa S, Kimura K, Ishizawa M, Ohara N, Uemura Y, Tsuchiya J

Endocrine journal12 Nov 2009Cited by 5 (Europe PMC)

PMID19907099 (opens in a new tab)DOI10.1507/endocrj.k09e-215 (opens in a new tab)PepBankPUB-19907099
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

10 results from studies that gave the peptide. 10 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, an intravenous GHRP‑2 bolus did not stimulate AVP secretion, with or without fasting.

    In plain wordsIn 10 healthy men, GHRP‑2 did not raise vasopressin release, whether they had fasted or not.

    Peptide
    GHRP-2
    Outcome
    No significant changeAVP secretion
    Study

    n = 10

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    AVP secretion was not stimulated by the GHRP-2 test with and without fasting.
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  2. 02HumanNon-randomized trialOther

    In 10 healthy men, hematocrit did not differ significantly before and after GHRP‑2 injection.

    In plain wordsIn 10 healthy men, GHRP‑2 injection did not change hematocrit.

    Peptide
    GHRP-2
    Outcome
    No significant changeHematocrit
    Study

    n = 10

    Outcome group
    Electrolyte balance · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    There were no significant differences in hematocrit, blood pressure and plasma osmolality
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  3. 03HumanNon-randomized trialSafety outcome

    In 10 healthy men, blood pressure did not differ significantly before and after GHRP‑2 injection.

    In plain wordsIn 10 healthy men, GHRP‑2 injection did not change blood pressure.

    Peptide
    GHRP-2
    Outcome
    No significant changeBlood pressure
    Study

    n = 10

    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    There were no significant differences in hematocrit, blood pressure and plasma osmolality
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  4. 04HumanNon-randomized trialOther

    In 10 healthy men, plasma osmolality did not differ significantly before and after GHRP‑2 injection.

    In plain wordsIn 10 healthy men, GHRP‑2 injection did not change plasma osmolality.

    Peptide
    GHRP-2
    Outcome
    No significant changePlasma osmolality
    Study

    n = 10

    Outcome group
    Electrolyte balance · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    There were no significant differences in hematocrit, blood pressure and plasma osmolality
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  5. 05HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, blood GH rose significantly (p<0.001) after intravenous GHRP‑2, with and without fasting.

    In plain wordsIn 10 healthy men, GHRP‑2 raised growth hormone in the blood, with and without fasting.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak blood GH
    Study

    n = 10

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    although significant (p<0.001) peak blood GH, and ACTH and PRL levels were observed 30 and 15 min after GHRP-2 injection with and without fasting, respectively
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  6. 06HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, blood ACTH rose significantly (p<0.001) after intravenous GHRP‑2, with and without fasting.

    In plain wordsIn 10 healthy men, GHRP‑2 raised ACTH in the blood, with and without fasting.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak blood ACTH
    Study

    n = 10

    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    although significant (p<0.001) peak blood GH, and ACTH and PRL levels were observed 30 and 15 min after GHRP-2 injection with and without fasting, respectively
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  7. 07HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, blood PRL rose significantly (p<0.001) after intravenous GHRP‑2, with and without fasting.

    In plain wordsIn 10 healthy men, GHRP‑2 raised prolactin in the blood, with and without fasting.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak blood PRL
    Study

    n = 10

    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    although significant (p<0.001) peak blood GH, and ACTH and PRL levels were observed 30 and 15 min after GHRP-2 injection with and without fasting, respectively
    1 context sentence
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  8. 08HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, the GHRP‑2-stimulated GH peak was higher with fasting than without fasting.

    In plain wordsIn 10 healthy men, the growth hormone peak after GHRP‑2 was higher when they had fasted than when they had not.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak GH, fasting vs not fasting
    Study

    n = 10

    Comparator
    GHRP-2 without fasting
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    and the maximal peaks were significantly (p<0.05) higher with fasting than without fasting.
    2 context sentences
    Summary · context
    though GH, ACTH and PRL levels were higher with than without fasting.
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  9. 09HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, the GHRP‑2-stimulated ACTH peak was higher with fasting than without fasting.

    In plain wordsIn 10 healthy men, the ACTH peak after GHRP‑2 was higher when they had fasted than when they had not.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak ACTH, fasting vs not fasting
    Study

    n = 10

    Comparator
    GHRP-2 without fasting
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    and the maximal peaks were significantly (p<0.05) higher with fasting than without fasting.
    2 context sentences
    Summary · context
    though GH, ACTH and PRL levels were higher with than without fasting.
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.
  10. 10HumanNon-randomized trialEfficacy outcome

    In 10 healthy men, the GHRP‑2-stimulated PRL peak was higher with fasting than without fasting.

    In plain wordsIn 10 healthy men, the prolactin peak after GHRP‑2 was higher when they had fasted than when they had not.

    Peptide
    GHRP-2
    Outcome
    IncreasePeak PRL, fasting vs not fasting
    Study

    n = 10

    Comparator
    GHRP-2 without fasting
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    100 microg · intravenous bolusAs given in this study (human).

    Source sentences

    Summary
    and the maximal peaks were significantly (p<0.05) higher with fasting than without fasting.
    2 context sentences
    Summary · context
    though GH, ACTH and PRL levels were higher with than without fasting.
    Summary · context
    To determine whether the GHRP-2 test is useful for assessing AVP secretion, blood ACTH, GH, FSH, LH, PRL, TSH and AVP levels, as well as glucose, osmolality, sodium and hematocrit, were measured before and 15, 30, 45 and 60 min after an intravenous bolus of 100 microg GHRP-2 in 10 healthy men with and without fasting.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

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