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Study · Randomized controlled trial · 2009

3 results

[The effect of tesofensine on body weight and body composition in obese subjects--secondary publication].

Nielsen AL, Larsen TM, Madsbad S, Breum L, Jensen TJ, Kroustrup JP, Astrup A

Ugeskrift for laeger1 Oct 2009Cited by 4 (Europe PMC)

PMID19824222 (opens in a new tab)PepBankPUB-19824222

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In obese people, tesofensine 0.25 mg produced mean weight reduction 4.5% higher than placebo.

    In plain wordsIn obese people, tesofensine 0.25 mg reduced weight more than placebo.

    Outcome
    DecreaseWeight reduction at 0.25 mg
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    0.25 mg daily · 24 weeksAs given in this study (human).

    Measurements

    Mean weight reduction above placebo
    4.5%
    0.25 mg

    Source sentences

    Summary
    Treatment with Tesofensine resulted in a mean weight reduction of 4.5, 9.2 and 10.6% higher than that of placebo for 0.25, 0.5 and 1.0 mg, respectively.
    1 context sentence
    Summary · context
    In total 203 obese persons were randomised to treatment with Tesofensine 0.25, 0.5, or 1.0 mg, or placebo daily for 24 weeks.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In obese people, tesofensine 0.5 mg produced mean weight reduction 9.2% higher than placebo.

    In plain wordsIn obese people, tesofensine 0.5 mg reduced weight more than placebo.

    Outcome
    DecreaseWeight reduction at 0.5 mg
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    0.5 mg daily · 24 weeksAs given in this study (human).

    Measurements

    Mean weight reduction above placebo
    9.2%
    0.5 mg

    Source sentences

    Summary
    Treatment with Tesofensine resulted in a mean weight reduction of 4.5, 9.2 and 10.6% higher than that of placebo for 0.25, 0.5 and 1.0 mg, respectively.
    1 context sentence
    Summary · context
    In total 203 obese persons were randomised to treatment with Tesofensine 0.25, 0.5, or 1.0 mg, or placebo daily for 24 weeks.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In obese people, tesofensine 1.0 mg produced mean weight reduction 10.6% higher than placebo.

    In plain wordsIn obese people, tesofensine 1.0 mg reduced weight more than placebo.

    Outcome
    DecreaseWeight reduction at 1.0 mg
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    1.0 mg daily · 24 weeksAs given in this study (human).

    Measurements

    Mean weight reduction above placebo
    10.6%
    1.0 mg

    Source sentences

    Summary
    Treatment with Tesofensine resulted in a mean weight reduction of 4.5, 9.2 and 10.6% higher than that of placebo for 0.25, 0.5 and 1.0 mg, respectively.
    1 context sentence
    Summary · context
    In total 203 obese persons were randomised to treatment with Tesofensine 0.25, 0.5, or 1.0 mg, or placebo daily for 24 weeks.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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