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Study · In vitro (cell-free) · 2010

2 results

A comparative study on the interactions of SMAP-29 with lipid monolayers.

Neville F, Ivankin A, Konovalov O, Gidalevitz D

Biochimica et biophysica acta2 Oct 2009Cited by 23 (Europe PMC)

PMID19800862 (opens in a new tab)PMCIDPMC2838942 (opens in a new tab)DOI10.1016/j.bbamem.2009.09.017 (opens in a new tab)PepBankPUB-19800862
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Activity measurement

    In lipid monolayers, LL‑37 discriminated against negatively charged phospholipids in a similar way to SMAP-29.

    In plain wordsIn lab tests with lipid films, LL‑37 and SMAP-29 acted on charged lipids in a similar way.

    Peptide
    LL-37
    Outcome
    Not applicableDiscrimination of negatively charged phospholipid monolayers
    Study

    n: not reported in source

    Phospholipid monolayers (Langmuir trough)
    Comparator
    SMAP-29
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The data show that SMAP-29 discriminates against negatively charged phospholipids in a similar way to LL-37.
    1 context sentence
    Summary · context
    Fluid phospholipid monolayers were formed in a Langmuir trough and subsequently studied with the X-ray scattering techniques of X-ray reflectivity and grazing incidence X-ray diffraction.
  2. 02LabIn vitro (cell-free)Activity measurement

    In lipid monolayers, about three and a half times fewer LL‑37 molecules than SMAP-29 molecules were needed to disrupt the monolayer.

    In plain wordsIn lab tests with lipid films, LL‑37 needed far fewer molecules than SMAP-29 to disrupt the film.

    Peptide
    LL-37
    Outcome
    Not applicablePeptide amount needed for monolayer disruption
    Study

    n: not reported in source

    Phospholipid monolayers (Langmuir trough)
    Comparator
    SMAP-29
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, it is even more interesting to note that despite a higher concentration of SMAP-29 near the monolayer, ensured by its greater charge as compared to LL-37, the amount of SMAP-29 needed to observe monolayer disruption was around three and a half times the number of molecules of LL-37 used to…
    1 context sentence
    Summary · context
    Fluid phospholipid monolayers were formed in a Langmuir trough and subsequently studied with the X-ray scattering techniques of X-ray reflectivity and grazing incidence X-ray diffraction.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:58 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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