Skip to content

Study · Randomized controlled trial · n = 27 · 2010

2 results

The effect of intranasal administration of oxytocin on fear recognition.

Fischer-Shofty M, Shamay-Tsoory SG, Harari H, Levkovitz Y

Neuropsychologia1 Jan 2010Cited by 136 (Europe PMC)

PMID19747930 (opens in a new tab)DOI10.1016/j.neuropsychologia.2009.09.003 (opens in a new tab)PepBankPUB-19747930
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men, a single intranasal oxytocin dose improved the ability to recognize fear compared with placebo.

    In plain wordsIn healthy men, one dose of oxytocin nasal spray improved recognition of fear in faces more than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseFear recognition
    Study

    n = 27

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    a single intranasal administration of oxytocin, as opposed to the placebo, improved the subjects' ability to recognize fear
    2 context sentences
    Summary · context
    In the present study, a double-blind placebo-controlled crossover design was used in a dynamic facial expression task, in order to assess the effects of administration of oxytocin on emotion recognition.
    Summary · context
    A single dose of oxytocin or a placebo was administered intranasally to 27 healthy male subjects 45 min prior to task performance.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy men, a single intranasal oxytocin dose did not improve recognition of emotions other than fear compared with placebo.

    In plain wordsIn healthy men, oxytocin nasal spray did not improve recognition of emotions other than fear compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeRecognition of other emotions
    Study

    n = 27

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasal · single doseAs given in this study (human).

    Source sentences

    Summary
    The results showed that a single intranasal administration of oxytocin, as opposed to the placebo, improved the subjects' ability to recognize fear, but not other emotions.
    2 context sentences
    Summary · context
    In the present study, a double-blind placebo-controlled crossover design was used in a dynamic facial expression task, in order to assess the effects of administration of oxytocin on emotion recognition.
    Summary · context
    A single dose of oxytocin or a placebo was administered intranasally to 27 healthy male subjects 45 min prior to task performance.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.