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Study · Not a test of the peptide alone · 2009

16 results

Efficacy of anti-aging products for periorbital wrinkles as measured by 3-D imaging.

Kaczvinsky JR, Griffiths CE, Schnicker MS, Li J

Journal of cosmetic dermatology1 Sept 2009Cited by 20 (Europe PMC)

PMID19735523 (opens in a new tab)DOI10.1111/j.1473-2165.2009.00444.x (opens in a new tab)PepBankPUB-19735523
Publisher pagePubMedAsk about this study
Jump to 16 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study16

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone16

In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  1. 01HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women with periorbital wrinkles, the combination daytime lotion improved crow's feet smoothness versus no treatment after 4 weeks.

    In plain wordsIn women, the combination daytime lotion improved crow's feet smoothness more than no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    IncreaseStudy 1 daytime lotion smoothness
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  2. 02HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women with periorbital wrinkles, the combination night cream improved crow's feet smoothness versus no treatment after 4 weeks.

    In plain wordsIn women, the combination night cream improved crow's feet smoothness more than no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    IncreaseStudy 1 night cream smoothness
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  3. 03HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women with periorbital wrinkles, the combination eye cream improved crow's feet smoothness versus no treatment after 4 weeks.

    In plain wordsIn women, the combination eye cream improved crow's feet smoothness more than no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    IncreaseStudy 1 eye cream smoothness
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  4. 04HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women, the combination daytime lotion significantly improved periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination daytime lotion reduced maximum wrinkle roughness more than no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 1 daytime lotion R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    After 4 weeks, the daytime SPF 30 lotion and night cream, but not the eye cream, were significantly better than no treatment at improving R(z).
    3 context sentences
    Summary · context
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  5. 05HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women, the combination night cream significantly improved periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination night cream reduced maximum wrinkle roughness more than no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 1 night cream R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    After 4 weeks, the daytime SPF 30 lotion and night cream, but not the eye cream, were significantly better than no treatment at improving R(z).
    3 context sentences
    Summary · context
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  6. 06HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women, the combination eye cream did not significantly improve periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination eye cream did not significantly reduce maximum wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    No significant changeStudy 1 eye cream R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    After 4 weeks, the daytime SPF 30 lotion and night cream, but not the eye cream, were significantly better than no treatment at improving R(z).
    3 context sentences
    Summary · context
    In Study 1, the daytime SPF 30 lotion, night cream, and eye cream significantly improved crow's feet smoothness after 4 weeks relative to no treatment.
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  7. 07HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination night cream significantly improved periorbital R(a) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination night cream reduced mean wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 night cream R(a)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  8. 08HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination night cream significantly improved periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination night cream reduced maximum wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 night cream R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  9. 09HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination eye cream significantly improved periorbital R(a) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination eye cream reduced mean wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 eye cream R(a)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  10. 10HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination eye cream significantly improved periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination eye cream reduced maximum wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 eye cream R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  11. 11HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination wrinkle treatment significantly improved periorbital R(a) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination wrinkle treatment reduced mean wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 wrinkle treatment R(a)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  12. 12HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination wrinkle treatment significantly improved periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination wrinkle treatment reduced maximum wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreaseStudy 2 wrinkle treatment R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  13. 13HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination daytime lotion did not significantly improve periorbital R(a) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination daytime lotion did not significantly reduce mean wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    No significant changeStudy 2 daytime lotion R(a)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  14. 14HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In Study 2 women, the combination daytime lotion did not significantly improve periorbital R(z) versus no treatment after 4 weeks.

    In plain wordsIn women, the combination daytime lotion did not significantly reduce maximum wrinkle roughness compared with no treatment after 4 weeks.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    No significant changeStudy 2 daytime lotion R(z)
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    In Study 2, the night cream, eye cream, and wrinkle treatment, but not the daytime SPF 30 lotion, significantly improved both R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  15. 15HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women with periorbital wrinkles, pooled data from the two studies showed three combination products were each significantly better than no treatment at improving R(a) after 4 weeks.

    In plain wordsIn women, three combination products reduced mean wrinkle roughness more than no treatment after 4 weeks in pooled data.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreasePooled R(a), three products
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    To increase power and precision of estimates, a meta-analysis was performed; the pooled data showed all three products were significantly better than no treatment at improving R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

  16. 16HumanNot a test of Matrixyl (palmitoyl pentapeptide-4) aloneRandomized controlled trialEfficacy outcome

    In women with periorbital wrinkles, pooled data from the two studies showed three combination products were each significantly better than no treatment at improving R(z) after 4 weeks.

    In plain wordsIn women, three combination products reduced maximum wrinkle roughness more than no treatment after 4 weeks in pooled data.

    Peptide
    Matrixyl (palmitoyl pentapeptide-4)
    Outcome
    DecreasePooled R(z), three products
    Study

    n: not reported in source

    Comparator
    No treatment
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    To increase power and precision of estimates, a meta-analysis was performed; the pooled data showed all three products were significantly better than no treatment at improving R(a) and R(z) after 4 weeks.
    2 context sentences
    Summary · context
    Two double-blind, randomized, controlled, split-face studies (n = 42, Study 1; n = 35, Study 2) were conducted in women 30-70 years old with moderate to distinct periorbital wrinkles.
    Summary · context
    Four test products containing niacinamide, the peptides Pal-KT and Pal-KTTKS, and carnosine were used and included a daytime SPF 30 lotion also containing antioxidants, a night cream, an eye cream also containing caffeine, and a wrinkle treatment containing retinyl propionate.

    In this study, Matrixyl (palmitoyl pentapeptide-4) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Matrixyl (palmitoyl pentapeptide-4).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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