In patients with Cushing's disease, GH release after GHRP‑6 increased after ketoconazole treatment, but not significantly.
In plain wordsIn people with Cushing's disease, the growth hormone response to GHRP‑6 rose after ketoconazole treatment, but the rise was not significant.
- Peptide
- GHRP-6
- Outcome
- No significant changeGH release after GHRP-6 before and after ketoconazole
- Study
n = 8
- Comparator
- Before ketoconazole
- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
Source sentences
GH release after GHRP-6 increased, although not significantly, while GH responsiveness to GHRH was unchanged.
1 context sentence(design, population, supporting numbers)
GH responses to ghrelin, GHRP-6, and GHRH of eight untreated patients with CD (mean age: 33.8+/-3.1 years; body mass index: 28.5+/-0.8 kg/m(2)) were evaluated before and after 3 and 6 months of ketoconazole treatment, and compared with 11 controls (32.1+/-2.5; 25.0+/-0.8).
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.