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Study · Animal study (in vivo) · mouse · 2009

1 result

NAP has no effect on spatial memory after short-term treatment in advanced stage Alzheimer's disease mouse model.

Van Dijck A, Van Dam D, De Deyn PP

Peptides5 Aug 2009

PMID19664667 (opens in a new tab)DOI10.1016/j.peptides.2009.07.024 (opens in a new tab)PepBankPUB-19664667
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In APP23 mice and wild-type littermates, NAP had no significant effect on Morris Water Maze performance versus saline.

    In plain wordsIn mice, NAP did not significantly change water maze performance compared with saline.

    Peptide
    Davunetide
    Outcome
    No significant changeMorris Water Maze performance
    Study

    Mousen: not reported in source

    APP23 Alzheimer's disease model and wild-type littermates
    Comparator
    Saline vehicle
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.3 microg/g body weight · intraperitoneal · 22 consecutive daysAs given in this study (Mouse).

    Source sentences

    Summary
    Treatment with NAP, however, did not exert any significant effects on MWM performance.
    2 context sentences
    Summary · context
    Twelve-month-old male heterozygous APP23 mice and their wild-type control littermates were intraperitoneally injected with 0.3 microg NAP/g body weight or with saline vehicle for 22 consecutive days.
    Summary · context
    Cognitive performance training in the Morris Water Maze (MWM) started on day 8 of treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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