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Study · In vitro (cells) · 2009

1 result

NAP protects against cyanide-related microtubule destruction.

Zemlyak I, Sapolsky R, Gozes I

Journal of neural transmission (Vienna, Austria : 1996)24 Jun 2009Cited by 13 (Europe PMC)

PMID19551468 (opens in a new tab)DOI10.1007/s00702-009-0252-7 (opens in a new tab)PepBankPUB-19551468
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In cerebral cortical cultures, NAP completely protected microtubules against sodium cyanide-induced destruction.

    In plain wordsIn lab tests, NAP completely protected microtubules compared with cyanide alone.

    Peptide
    Davunetide
    Outcome
    IncreaseMicrotubule preservation
    Study

    n: not reported in source

    Cerebral cortical cultures
    Comparator
    Sodium cyanide alone
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    10(-14)-10(-12) MAs given in this study.

    Source sentences

    Summary
    When sodium cyanide was added together with NAP (10(-14)-10(-12) M), complete protection was observed.
    2 context sentences
    Summary · context
    The current study explored the effect of NAP on cyanide-induced microtubule destruction in cerebral cortical cultures.
    Summary · context
    Sodium cyanide (6.8 mM) reduced the number of neurons containing intact microtubules as identified by bIII-tubulin immunostaining.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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