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Study · Measured the body's own peptide · 2009

3 results

Characterization of the oxytocin system regulating affiliative behavior in female prairie voles.

Ross HE, Cole CD, Smith Y, Neumann ID, Landgraf R, Murphy AZ, Young LJ

Neuroscience29 May 2009Cited by 252 (Europe PMC)

PMID19482070 (opens in a new tab)PMCIDPMC2744157 (opens in a new tab)DOI10.1016/j.neuroscience.2009.05.055 (opens in a new tab)PepBankPUB-19482070
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In female prairie voles, the body's own extracellular oxytocin rose in the nucleus accumbens during unrestricted interaction with a male.

    In plain wordsIn female prairie voles, the body's own oxytocin rose in a brain region during contact with a male.

    Peptide
    Oxytocin
    Outcome
    IncreaseExtracellular oxytocin in nucleus accumbens during male interaction
    Study

    prairie volen: not reported in source

    Female prairie voles, nucleus accumbens
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Here we show for the first time that extracellular concentrations of oxytocin are increased in the nucleus accumbens of female prairie vole during unrestricted interactions with a male.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In voles, mice and rats, the distribution of the body's own oxytocin-immunoreactive fibers in the nucleus accumbens was conserved across species.

    In plain wordsIn voles, mice and rats, fibers that carry the body's own oxytocin had a similar spread in one brain region.

    Peptide
    Oxytocin
    Outcome
    Not applicableDistribution of oxytocin-immunoreactive fibers in nucleus accumbens
    Study

    prairie vole, mouse, ratn: not reported in source

    Brain tissue
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    We further show that the distribution of oxytocin-immunoreactive fibers in the nucleus accumbens is conserved in voles, mice and rats, despite remarkable species differences in oxytocin receptor binding in the region.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In prairie voles, tracer studies indicated that oxytocin-immunoreactive fibers in the nucleus accumbens likely originate from paraventricular and supraoptic hypothalamic neurons.

    In plain wordsIn prairie voles, the fibers that carry the body's own oxytocin in one brain region likely come from two hypothalamic areas.

    Peptide
    Oxytocin
    Outcome
    Not applicableOrigin of nucleus accumbens oxytocin fibers
    Study

    prairie volen: not reported in source

    Retrograde tracer tracing in brain
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Using a combination of site-specific and peripheral infusions of the retrograde tracer Fluorogold, we demonstrate that the nucleus accumbens oxytocin-immunoreactive fibers likely originate from paraventricular and supraoptic hypothalamic neurons.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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