Skip to content

Study · Not a test of the peptide alone · 2009

3 results

Variation in oxytocin receptor density in the nucleus accumbens has differential effects on affiliative behaviors in monogamous and polygamous voles.

Ross HE, Freeman SM, Spiegel LL, Ren X, Terwilliger EF, Young LJ

The Journal of neuroscience : the official journal of the Society for Neuroscience1 Feb 2009Cited by 248 (Europe PMC)

PMID19193878 (opens in a new tab)PMCIDPMC2768419 (opens in a new tab)DOI10.1523/jneurosci.5039-08.2009 (opens in a new tab)PepBankPUB-19193878
Read at sourcePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In female prairie voles, oxytocin receptor overexpression in the nucleus accumbens accelerated partner preference formation after cohabitation with a male.

    In plain wordsIn female prairie voles, more oxytocin receptors in a brain area sped up bonding with a male partner.

    Peptide
    Oxytocin
    Outcome
    IncreasePartner preference formation in female prairie voles
    Study

    prairie volen: not reported in source

    viral vector overexpression of oxytocin receptor in the nucleus accumbens
    Outcome group
    Social behavior and cognition · Nervous system and cognition

    Source sentences

    Summary
    Adult female prairie voles that overexpress oxytocin receptor in the nucleus accumbens displayed accelerated partner preference formation after cohabitation with a male
    1 context sentence
    Summary · context
    Here we used adeno-associated viral vector gene transfer to examine the functional relationship between accumbal oxytocin receptor density and social behavior in prairie and meadow voles.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In female prairie voles, oxytocin receptor overexpression in the nucleus accumbens did not enhance alloparental behavior.

    In plain wordsIn female prairie voles, more oxytocin receptors in a brain area did not increase care for young animals.

    Peptide
    Oxytocin
    Outcome
    No significant changeAlloparental behavior in female prairie voles
    Study

    prairie volen: not reported in source

    viral vector overexpression of oxytocin receptor in the nucleus accumbens
    Outcome group
    Social behavior and cognition · Nervous system and cognition

    Source sentences

    Summary
    but did not display enhanced alloparental behavior.
    1 context sentence
    Summary · context
    Here we used adeno-associated viral vector gene transfer to examine the functional relationship between accumbal oxytocin receptor density and social behavior in prairie and meadow voles.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In nonmonogamous meadow voles, introducing oxytocin receptor into the nucleus accumbens did not facilitate partner preference.

    In plain wordsIn meadow voles, adding oxytocin receptors to a brain area did not make them form partner bonds.

    Peptide
    Oxytocin
    Outcome
    No significant changePartner preference in meadow voles
    Study

    meadow volen: not reported in source

    viral vector overexpression of oxytocin receptor in the nucleus accumbens
    Outcome group
    Social behavior and cognition · Nervous system and cognition

    Source sentences

    Summary
    However, partner preference was not facilitated in nonmonogamous meadow voles by introducing oxytocin receptor into the nucleus accumbens.
    1 context sentence
    Summary · context
    Here we used adeno-associated viral vector gene transfer to examine the functional relationship between accumbal oxytocin receptor density and social behavior in prairie and meadow voles.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.