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Study · Animal study (in vivo) · mouse · 2008

4 results

Audiogenic epilepsy in young mice of different strains after neonatal semax treatment.

Boyarshinova OS, Perepelkina OV, Markina NV, Poletaeva II

Bulletin of experimental biology and medicine1 Jul 2008

PMID19145359 (opens in a new tab)DOI10.1007/s10517-008-0212-5 (opens in a new tab)PepBankPUB-19145359
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In one-month-old DBA/2J mice, neonatal Semax significantly reduced predisposition to audiogenic epilepsy.

    In plain wordsIn mice, Semax given soon after birth reduced sound-triggered seizure risk in one strain at one month.

    Peptide
    Semax
    Outcome
    DecreaseAudiogenic epilepsy predisposition in DBA/2J mice
    Study

    mousen: not reported in source

    5 inbred strains, audiogenic epilepsy
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · day 2 to day 7 of lifeAs given in this study (mouse).

    Source sentences

    Summary
    Neonatal (from day 2 to day 7 of life) injection of neuropeptide semax to mice of 5 inbred strains significantly reduced predisposition to audiogenic epilepsy in only one-month-old DBA/2J mice, which manifested in changes in the mean audiogenic sensitivity score and percentage of animals dead as a r…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In one-month-old DBA/2J mice, neonatal Semax changed the mean audiogenic sensitivity score.

    In plain wordsIn mice, Semax given soon after birth changed the sound-sensitivity score in one strain.

    Peptide
    Semax
    Outcome
    Direction not reportedMean audiogenic sensitivity score in DBA/2J mice
    Study

    mousen: not reported in source

    5 inbred strains, audiogenic epilepsy
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · day 2 to day 7 of lifeAs given in this study (mouse).

    Source sentences

    Summary
    Neonatal (from day 2 to day 7 of life) injection of neuropeptide semax to mice of 5 inbred strains significantly reduced predisposition to audiogenic epilepsy in only one-month-old DBA/2J mice, which manifested in changes in the mean audiogenic sensitivity score and percentage of animals dead as a r…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In one-month-old DBA/2J mice, neonatal Semax changed the percentage of animals that died after acoustic stimulation.

    In plain wordsIn mice, Semax given soon after birth changed the share of animals that died after loud sound in one strain.

    Peptide
    Semax
    Outcome
    Direction not reportedDeath after acoustic stimulation in DBA/2J mice
    Study

    mousen: not reported in source

    5 inbred strains, audiogenic epilepsy
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · day 2 to day 7 of lifeAs given in this study (mouse).

    Source sentences

    Summary
    Neonatal (from day 2 to day 7 of life) injection of neuropeptide semax to mice of 5 inbred strains significantly reduced predisposition to audiogenic epilepsy in only one-month-old DBA/2J mice, which manifested in changes in the mean audiogenic sensitivity score and percentage of animals dead as a r…
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In mice of the other four inbred strains, neonatal Semax did not significantly reduce predisposition to audiogenic epilepsy.

    In plain wordsIn mice, Semax given soon after birth did not reduce sound-triggered seizure risk in the other four strains.

    Peptide
    Semax
    Outcome
    No significant changeAudiogenic epilepsy predisposition in the other four strains
    Study

    mousen: not reported in source

    5 inbred strains, audiogenic epilepsy
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · day 2 to day 7 of lifeAs given in this study (mouse).

    Source sentences

    Summary
    Neonatal (from day 2 to day 7 of life) injection of neuropeptide semax to mice of 5 inbred strains significantly reduced predisposition to audiogenic epilepsy in only one-month-old DBA/2J mice, which manifested in changes in the mean audiogenic sensitivity score and percentage of animals dead as a r…

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 10:21 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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