Skip to content

Study · Animal study (in vivo) · mouse · 2008

3 results

Immunocorrecting properties of GB-115 dipeptide.

Shipaeva EV, Kovalenko LP, Khaidukov SV, Kolik LG, Gudasheva TA, Durnev AD, Durnev AD, Seredenin SB

Bulletin of experimental biology and medicine1 May 2008Cited by 1 (Europe PMC)

PMID19145294 (opens in a new tab)DOI10.1007/s10517-008-0153-z (opens in a new tab)PepBankPUB-19145294
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In intact mice, GB‑115 stimulated phagocytic activity of peritoneal macrophages.

    In plain wordsIn mice, GB‑115 increased the phagocytic activity of peritoneal macrophages.

    Peptide
    GB-115
    Outcome
    IncreasePeritoneal macrophage phagocytic activity
    Study

    mousen: not reported in source

    Intact mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    0.1-10 mg/kgAs given in this study (mouse).

    Source sentences

    Summary
    GB-115 in doses of 0.1-10 mg/kg stimulated phagocytic activity of peritoneal macrophages and humoral immune response in intact mice.
    1 context sentence
    Summary · context
    We studied the effects of a new dipeptide with anxiolytic activity (GB-115, N-phenylhexanoyl-glycyl-L-tryptophan amide) on parameters of the immune in intact mice and in animals with secondary immunodeficiency caused by cyclophosphamide.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In intact mice, GB‑115 stimulated the humoral immune response.

    In plain wordsIn mice, GB‑115 increased the humoral immune response.

    Peptide
    GB-115
    Outcome
    IncreaseHumoral immune response
    Study

    mousen: not reported in source

    Intact mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    0.1-10 mg/kgAs given in this study (mouse).

    Source sentences

    Summary
    GB-115 in doses of 0.1-10 mg/kg stimulated phagocytic activity of peritoneal macrophages and humoral immune response in intact mice.
    1 context sentence
    Summary · context
    We studied the effects of a new dipeptide with anxiolytic activity (GB-115, N-phenylhexanoyl-glycyl-L-tryptophan amide) on parameters of the immune in intact mice and in animals with secondary immunodeficiency caused by cyclophosphamide.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In animals with secondary immunodeficiency, GB‑115 exhibited immunocorrecting activity.

    In plain wordsIn mice with secondary immunodeficiency, GB‑115 showed immunocorrecting activity.

    Peptide
    GB-115
    Outcome
    Direction not reportedImmunocorrecting activity
    Study

    mousen: not reported in source

    Cyclophosphamide-induced secondary immunodeficiency
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    GB-115 exhibited immunocorrecting activity in animals with secondary immunodeficiency.
    1 context sentence
    Summary · context
    We studied the effects of a new dipeptide with anxiolytic activity (GB-115, N-phenylhexanoyl-glycyl-L-tryptophan amide) on parameters of the immune in intact mice and in animals with secondary immunodeficiency caused by cyclophosphamide.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.