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Study · Randomized controlled trial · 2009

4 results

Oxytocin makes a face in memory familiar.

Rimmele U, Hediger K, Heinrichs M, Klaver P

The Journal of neuroscience : the official journal of the Society for Neuroscience1 Jan 2009Cited by 288 (Europe PMC)

PMID19129382 (opens in a new tab)PMCIDPMC6664913 (opens in a new tab)DOI10.1523/jneurosci.4260-08.2009 (opens in a new tab)PepBankPUB-19129382
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In humans, intranasal oxytocin improved recognition memory for faces.

    In plain wordsIn people, oxytocin nasal spray improved memory for recognising faces.

    Peptide
    Oxytocin
    Outcome
    IncreaseRecognition memory for faces
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Here, we show that, in humans, the evolutionarily highly conserved neuropeptide oxytocin, after intranasal administration, specifically improves recognition memory for faces, but not for nonsocial stimuli.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In humans, intranasal oxytocin did not improve recognition memory for nonsocial stimuli.

    In plain wordsIn people, oxytocin nasal spray did not improve memory for recognising objects other than faces.

    Peptide
    Oxytocin
    Outcome
    No significant changeRecognition memory for nonsocial stimuli
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Here, we show that, in humans, the evolutionarily highly conserved neuropeptide oxytocin, after intranasal administration, specifically improves recognition memory for faces, but not for nonsocial stimuli.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In humans, with increased oxytocin levels previously presented faces were more correctly assessed as known.

    In plain wordsIn people given oxytocin, faces seen before were more often correctly judged as known.

    Peptide
    Oxytocin
    Outcome
    IncreaseFamiliarity judgements of previously presented faces
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    With increased oxytocin levels, previously presented faces were more correctly assessed as "known," whereas the ability of recollecting faces was unchanged.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In humans, intranasal oxytocin did not change the ability to recollect faces.

    In plain wordsIn people, oxytocin nasal spray did not change the ability to recall details about faces.

    Peptide
    Oxytocin
    Outcome
    No significant changeRecollection of faces
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    With increased oxytocin levels, previously presented faces were more correctly assessed as "known," whereas the ability of recollecting faces was unchanged.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · 1 completed · source ClinicalTrials.gov (opens in a new tab)

CompletedEarly phase 1NCT03211013

Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD

Palo Alto Veterans Institute for Researchn = 1710 Jul 2017 to 9 Jun 2021

Posttraumatic Stress Disorder

Trial pageClinicalTrials.govUpdated 10 Jun 2021

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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