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Study · In vitro (cells) · 2008

3 results

Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling.

Chen S, Charness ME

Proceedings of the National Academy of Sciences of the United States of America1 Dec 2008Cited by 38 (Europe PMC)

PMID19047645 (opens in a new tab)PMCIDPMC2604983 (opens in a new tab)DOI10.1073/pnas.0807758105 (opens in a new tab)PepBankPUB-19047645
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In cerebellar granule neurons, NAP potentiated axon outgrowth.

    In plain wordsIn cells, NAP increased axon growth.

    Peptide
    Davunetide
    Outcome
    IncreaseAxon outgrowth
    Study

    n: not reported in source

    Cerebellar granule neurons
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    NAPVSIPQ (NAP), a potent active fragment of ADNP, potentiated axon outgrowth in cerebellar granule neurons by activating the sequential tyrosine phosphorylation of Fyn kinase and the scaffold protein Crk-associated substrate (Cas).
  2. 02LabIn vitro (cells)Mechanism

    In cerebellar granule neurons, NAP activated Fyn kinase tyrosine phosphorylation.

    In plain wordsIn cells, NAP activated phosphorylation of Fyn kinase.

    Peptide
    Davunetide
    Outcome
    IncreaseFyn kinase tyrosine phosphorylation
    Study

    n: not reported in source

    Cerebellar granule neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    NAPVSIPQ (NAP), a potent active fragment of ADNP, potentiated axon outgrowth in cerebellar granule neurons by activating the sequential tyrosine phosphorylation of Fyn kinase and the scaffold protein Crk-associated substrate (Cas).
  3. 03LabIn vitro (cells)Mechanism

    In cerebellar granule neurons, NAP activated tyrosine phosphorylation of Crk-associated substrate.

    In plain wordsIn cells, NAP activated phosphorylation of the scaffold protein Cas.

    Peptide
    Davunetide
    Outcome
    IncreaseCas tyrosine phosphorylation
    Study

    n: not reported in source

    Cerebellar granule neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    NAPVSIPQ (NAP), a potent active fragment of ADNP, potentiated axon outgrowth in cerebellar granule neurons by activating the sequential tyrosine phosphorylation of Fyn kinase and the scaffold protein Crk-associated substrate (Cas).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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