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Study · Non-randomized trial · 2008

6 results

[Characteristics of ladasten effect in neurasthenia patients with various EEG parameters].

Neznamov GG, Bochkarev VK, Siuniakov SA, Grishin SA

Eksperimental'naia i klinicheskaia farmakologiia1 Jul 2008Cited by 2 (Europe PMC)

PMID18819436 (opens in a new tab)PepBankPUB-18819436
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. 6 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In anxiety-asthenic patients with marked alpha rhythm, ladasten showed predominantly psychostimulant action.

    In plain wordsIn patients with marked alpha rhythm, ladasten showed predominantly stimulant effects.

    Peptide
    Bromantane
    Outcome
    IncreasePsychostimulant action
    Study

    n: not reported in source

    Outcome group
    Anxiety and mood · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that, in patients with marked alpha rhythm corresponding to asthenic personal traits, ladasten exhibits predominantly a psychostimulant action assessed by clinical rating scales, which is accompanied by high frequencies of alpha rhythm increase and beta 1 and beta 2 rhythms decrease.
    2 context sentences
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.
  2. 02HumanNon-randomized trialEfficacy outcome

    In patients with marked alpha rhythm, ladasten increased high-frequency alpha rhythm.

    In plain wordsIn patients with marked alpha rhythm, ladasten increased high-frequency alpha activity.

    Peptide
    Bromantane
    Outcome
    IncreaseHigh-frequency alpha rhythm
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that, in patients with marked alpha rhythm corresponding to asthenic personal traits, ladasten exhibits predominantly a psychostimulant action assessed by clinical rating scales, which is accompanied by high frequencies of alpha rhythm increase and beta 1 and beta 2 rhythms decrease.
    2 context sentences
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.
  3. 03HumanNon-randomized trialEfficacy outcome

    In patients with marked alpha rhythm, ladasten decreased beta 1 rhythm.

    In plain wordsIn patients with marked alpha rhythm, ladasten decreased beta 1 activity.

    Peptide
    Bromantane
    Outcome
    DecreaseBeta 1 rhythm in marked-alpha patients
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that, in patients with marked alpha rhythm corresponding to asthenic personal traits, ladasten exhibits predominantly a psychostimulant action assessed by clinical rating scales, which is accompanied by high frequencies of alpha rhythm increase and beta 1 and beta 2 rhythms decrease.
    2 context sentences
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.
  4. 04HumanNon-randomized trialEfficacy outcome

    In patients with marked alpha rhythm, ladasten decreased beta 2 rhythm.

    In plain wordsIn patients with marked alpha rhythm, ladasten decreased beta 2 activity.

    Peptide
    Bromantane
    Outcome
    DecreaseBeta 2 rhythm in marked-alpha patients
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It was established that, in patients with marked alpha rhythm corresponding to asthenic personal traits, ladasten exhibits predominantly a psychostimulant action assessed by clinical rating scales, which is accompanied by high frequencies of alpha rhythm increase and beta 1 and beta 2 rhythms decrease.
    2 context sentences
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.
  5. 05HumanNon-randomized trialEfficacy outcome

    In patients with reduced alpha rhythm, ladasten increased low-frequency alpha rhythm.

    In plain wordsIn patients with reduced alpha rhythm, ladasten increased low-frequency alpha activity.

    Peptide
    Bromantane
    Outcome
    IncreaseLow-frequency alpha rhythm
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In patients with reduced alpha rhythm and the EEG type corresponding to asthenic personal traits, ladasten action was characterized by an increase of alpha-rhythm low frequencies and the opposite reaction of beta 1 and beta 2 rhythms, whose are typical for the EEG pattern of anxiolytic effect.
    2 context sentences
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.
  6. 06HumanNon-randomized trialEfficacy outcome

    In patients with reduced alpha rhythm, ladasten action included an opposite reaction of beta 1 and beta 2 rhythms, with the direction not stated clearly.

    In plain wordsIn patients with reduced alpha rhythm, the study described an opposite beta 1 and beta 2 reaction to ladasten without stating its direction clearly.

    Peptide
    Bromantane
    Outcome
    Direction not reportedBeta 1 and beta 2 rhythms in reduced-alpha patients
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In patients with reduced alpha rhythm and the EEG type corresponding to asthenic personal traits, ladasten action was characterized by an increase of alpha-rhythm low frequencies and the opposite reaction of beta 1 and beta 2 rhythms, whose are typical for the EEG pattern of anxiolytic effect.
    3 context sentences
    Summary · context
    It was established that, in patients with marked alpha rhythm corresponding to asthenic personal traits, ladasten exhibits predominantly a psychostimulant action assessed by clinical rating scales, which is accompanied by high frequencies of alpha rhythm increase and beta 1 and beta 2 rhythms decrease.
    Summary · context
    Clinical and electroencephalographic (EEG) analysis ofladasten action in anxiety-asthenic patients with respect to their EEG-defined individual typological characteristics was carried out.
    Summary · context
    Primary psychopathologic disorders and ladasten effects were assessed by objective classification methods (factor and cluster analyses), and individual EEG types characterized by marked or reduced alpha rhythm were determined.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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