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Study · Measured the body's own peptide · 2008

3 results

The outcome of tactile touch on oxytocin in intensive care patients: a randomised controlled trial.

Henricson M, Berglund AL, Määttä S, Ekman R, Segesten K

Journal of clinical nursing1 Oct 2008Cited by 17 (Europe PMC)

PMID18808627 (opens in a new tab)DOI10.1111/j.1365-2702.2008.02324.x (opens in a new tab)PepBankPUB-18808627
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In intensive care patients, the change in arterial oxytocin from day 1 to day 6 did not differ significantly between the tactile touch and control groups.

    In plain wordsIn intensive care patients, the body's own oxytocin change over six days did not differ significantly between touch and standard rest.

    Peptide
    Oxytocin
    Outcome
    No significant changeDifference in oxytocin change between tactile touch and control groups
    Study

    n = 44

    Comparator
    Standard treatment (an hour of rest)
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Mean difference in change
    23.4 pM
    tactile touch versus control

    Source sentences

    Summary
    There were no significant differences in changes between day 1 and day 6 when comparing the intervention group and control group, mean 23.4 pM (95% CI -20.2-67.0).
    1 context sentence
    Summary · context
    Forty-four patients from two general intensive care units, were randomly assigned to either tactile touch (n = 21) or standard treatment--an hour of rest (n = 23).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelRandomized controlled trialOther

    In intensive care patients given standard treatment (an hour of rest), arterial oxytocin fell significantly from day 1 to day 6.

    In plain wordsIn intensive care patients given standard rest, the body's own oxytocin level fell over six days.

    Peptide
    Oxytocin
    Outcome
    DecreaseChange in arterial oxytocin from day 1 to day 6 in the control group
    Study

    n = 23

    Comparator
    Standard treatment (an hour of rest)
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Mean decrease in oxytocin
    26.4 pM
    control group

    Source sentences

    Summary
    In the control group, there was a significant (p = 0.01) decrease in oxytocin levels from day 1 to day 6, mean 26.4 pM (SD 74.1).
    1 context sentence
    Summary · context
    Forty-four patients from two general intensive care units, were randomly assigned to either tactile touch (n = 21) or standard treatment--an hour of rest (n = 23).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelRandomized controlled trialOther

    In intensive care patients, arterial oxytocin showed no significant mean change from day 1 to day 6 in the five-day tactile touch group.

    In plain wordsIn intensive care patients, the body's own oxytocin level did not change significantly over six days with tactile touch.

    Peptide
    Oxytocin
    Outcome
    No significant changeChange in arterial oxytocin from day 1 to day 6 in the tactile touch group
    Study

    n = 21

    Comparator
    Standard treatment (an hour of rest)
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    Mean change in oxytocin
    −3 pM
    tactile touch group

    Source sentences

    Summary
    No significant mean changes in oxytocin levels were found from day 1 to day 6 in the intervention group (mean -3.0 pM, SD 16.8).
    1 context sentence
    Summary · context
    Forty-four patients from two general intensive care units, were randomly assigned to either tactile touch (n = 21) or standard treatment--an hour of rest (n = 23).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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