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Study · Not a test of the peptide alone · 2009

4 results

Expression of thymosin alpha1 concatemer in transgenic tomato (Solanum lycopersicum) fruits.

Chen Y, Wang A, Zhao L, Shen G, Cui L, Tang K

Biotechnology and applied biochemistry1 Apr 2009Cited by 10 (Europe PMC)

PMID18752465 (opens in a new tab)DOI10.1042/ba20080054 (opens in a new tab)PepBankPUB-18752465
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cells)Activity measurement

    In mouse splenic lymphocytes in vitro, tomato-derived 4 x Talpha1 protein stimulated proliferation.

    In plain wordsIn lab tests with mouse immune cells, tomato-made thymosin alpha1 concatemer protein stimulated cell growth.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseStimulation of mouse splenic lymphocyte proliferation
    Study

    mousen: not reported in source

    mouse splenic lymphocytes
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    the 4 x Talpha1 protein derived from transgenic tomatoes exhibited bioactivity that can stimulate the proliferation of mice splenic lymphocytes in vitro

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cells)Activity measurement

    In mouse splenic lymphocytes in vitro, the specific activity of Talpha1 protein from tomato was higher than that from the synthetic E. coli system.

    In plain wordsIn lab tests with mouse immune cells, tomato-made Talpha1 protein was more active than Talpha1 made in E. coli.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseSpecific activity of tomato-derived versus E. coli-derived Talpha1
    Study

    mousen: not reported in source

    mouse splenic lymphocytes
    Comparator
    Talpha1 from the synthetic Escherichia coli system
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    the specific activity of Talpha1 protein from the artificial system was higher than that from the synthetic Escherichia coli system.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  3. 03LabNot a test of Thymosin alpha-1 aloneOther designOther

    In transgenic tomato, the 4 x Talpha1 gene was transcribed specifically in fruits.

    In plain wordsIn lab-grown transgenic tomato, the thymosin alpha1 gene copies were active only in the fruit.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicable4 x Talpha1 gene transcription in tomato fruits
    Study

    Solanum lycopersicumn: not reported in source

    transgenic tomato expressing 4 x Talpha1
    Outcome group
    Synthesis and manufacturing · Pharmacology

    Source sentences

    Summary
    RT-PCR (reverse transcription-PCR) analysis showed that the 4 x Talpha1 gene was transcribed specifically in tomato [Solanum lycopersicum (formerly Lycopersicon esculentum)] fruits.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  4. 04LabNot a test of Thymosin alpha-1 aloneOther designOther

    In transgenic tomato, the 4 x Talpha1 protein reached a maximum of 6.098 microg/g fresh weight in mature fruit.

    In plain wordsIn lab-grown transgenic tomato, ripe fruit made measurable amounts of the thymosin alpha1 concatemer protein.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicable4 x Talpha1 protein content in mature tomato fruit
    Study

    Solanum lycopersicumn: not reported in source

    transgenic tomato expressing 4 x Talpha1
    Outcome group
    Synthesis and manufacturing · Pharmacology

    Measurements

    4 x Talpha1 protein content
    6.098 microg/g fresh weight
    mature tomato fruit

    Source sentences

    Summary
    ELISA analysis showed that the content of the 4 x Talpha1 protein reached a maximum of 6.098 microg/g fresh weight in mature tomato fruit.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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