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Study · Animal study (in vivo) · monkey · 2008

6 results

[Compensatory and antiamnestic effects of heptapeptide Selank in monkeys].

The source lists no authors.

Zhurnal evoliutsionnoi biokhimii i fiziologii1 May 2008Cited by 1 (Europe PMC)

PMID18727417 (opens in a new tab)PepBankPUB-18727417
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, intranasal selank produced long-term elimination of fear and aggression.

    In plain wordsIn monkeys with neurosis, selank given through the nose removed fear and aggression for a long time.

    Peptide
    Selank
    Outcome
    DecreaseFear and aggression
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    New data have been obtained which indicate that an intranasal administration of Selank produces long-term changes of the monkeys' behavior disturbed during neurosis: elimination of fear and aggression and an increase of orientational-explorative activity as well as facilitation of handling reactions…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, intranasal selank increased orientational-explorative activity.

    In plain wordsIn monkeys with neurosis, selank given through the nose increased exploring behavior.

    Peptide
    Selank
    Outcome
    IncreaseOrientational-explorative activity
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    New data have been obtained which indicate that an intranasal administration of Selank produces long-term changes of the monkeys' behavior disturbed during neurosis: elimination of fear and aggression and an increase of orientational-explorative activity as well as facilitation of handling reactions…
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, intranasal selank facilitated handling reactions and communicational relations.

    In plain wordsIn monkeys with neurosis, selank given through the nose made handling and social contact easier.

    Peptide
    Selank
    Outcome
    IncreaseHandling reactions and communicational relations
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    New data have been obtained which indicate that an intranasal administration of Selank produces long-term changes of the monkeys' behavior disturbed during neurosis: elimination of fear and aggression and an increase of orientational-explorative activity as well as facilitation of handling reactions…
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, selank was followed by a long compensation of disturbed psychic functions, including memory processes.

    In plain wordsIn monkeys with neurosis, selank was followed by long-lasting recovery of disturbed mental functions, including memory.

    Peptide
    Selank
    Outcome
    IncreaseMemory processes disturbed by neurosis
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    It has been established that on the background of the Selank there occurs a long compensation of disturbed psychic functions (processes of memory) and of homeostatic parameters.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, selank was followed by a long compensation of disturbed homeostatic parameters.

    In plain wordsIn monkeys with neurosis, selank was followed by long-lasting recovery of disturbed body regulation measures.

    Peptide
    Selank
    Outcome
    Direction not reportedHomeostatic parameters disturbed by neurosis
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Overall treatment effect · Whole body
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    It has been established that on the background of the Selank there occurs a long compensation of disturbed psychic functions (processes of memory) and of homeostatic parameters.
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In monkeys with neurosis, selank effects did not depend on the type of neurotic disturbance and were long-term, unlike thyroliberin and ACTH4-10.

    In plain wordsIn monkeys, selank effects lasted long and did not depend on the type of neurosis, unlike thyroliberin and ACTH4-10.

    Peptide
    Selank
    Outcome
    Not applicableDependence of antistressor effect on type of neurotic disturbance
    Study

    monkeyn: not reported in source

    Monkeys with experimental neurosis
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (monkey).

    Source sentences

    Summary
    It has been shown that unlike the earlier studied neurohormones (thyroliberin and ACTH4-10), the antistressor Selank effects do not depend on the type of neurotic disturbances and have long-term compensatory character.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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