Skip to content

Study · Animal study (in vivo) · rat · 2008

1 result

Potential role of lipin-1 in exercise-induced mitochondrial biogenesis.

Higashida K, Higuchi M, Terada S

Biochemical and biophysical research communications24 Jul 2008Cited by 32 (Europe PMC)

PMID18656451 (opens in a new tab)DOI10.1016/j.bbrc.2008.07.079 (opens in a new tab)PepBankPUB-18656451
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rat triceps muscle, lipin-1 mRNA expression increased significantly at 6h after AICAR injection.

    In plain wordsIn rats, AICAR injection increased lipin-1 messenger RNA in triceps muscle at 6h.

    Peptide
    AICAR (acadesine)
    Outcome
    IncreaseLipin-1 mRNA expression
    Study

    ratn: not reported in source

    triceps muscle
    Outcome group
    Mitochondrial function · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneous · 6hAs given in this study (rat).

    Source sentences

    Summary
    Finally, lipin-1 mRNA expression in rat triceps muscle was significantly elevated at 6h after subcutaneous injections of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) or clenbuterol, which are 5'-AMP-activated protein kinase (AMPK) and beta2-adrenergic receptor (beta2-AR) activators, respectively.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.