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Study · Animal study (in vivo) · mouse · 2007

5 results

[Genotype-dependent mice behavior in cognitive tasks. Effect of noopept].

Bel'nik AP, Ostrovskaia RU, Poletaeva II

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova1 Nov 2007

PMID18592707 (opens in a new tab)PepBankPUB-18592707
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In BALB/c mice, noopept improved long-term memory in the Morris test.

    In plain wordsIn mice of the BALB/c strain, noopept improved long-term maze memory.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseLong-term Morris maze memory
    Study

    mousen: not reported in source

    BALB/c mice
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitoneal · 15 min before learningAs given in this study (mouse).

    Source sentences

    Summary
    Its administration (0.5 mg/kg i.p., 15 min before learning) improved the long-term memory in Morris test in BALB/c mice but failed to produce any improvement in C57BL/6J.
    1 context sentence
    Summary · context
    The effect of nootropic drug Noopept (GVS-111, N-phenil-acetyl-L-prolylglycin ethyl ether) was shown to be genotype-dependent.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In C57BL/6J mice, noopept did not improve long-term memory in the Morris test.

    In plain wordsIn mice of the C57BL/6J strain, noopept did not improve long-term maze memory.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeLong-term Morris maze memory
    Study

    mousen: not reported in source

    C57BL/6J mice
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.5 mg/kg · intraperitoneal · 15 min before learningAs given in this study (mouse).

    Source sentences

    Summary
    Its administration (0.5 mg/kg i.p., 15 min before learning) improved the long-term memory in Morris test in BALB/c mice but failed to produce any improvement in C57BL/6J.
    1 context sentence
    Summary · context
    The effect of nootropic drug Noopept (GVS-111, N-phenil-acetyl-L-prolylglycin ethyl ether) was shown to be genotype-dependent.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In C57BL/6J mice, noopept increased the proportion of correct stimulus-movement extrapolation task solutions.

    In plain wordsIn mice of the C57BL/6J strain, noopept increased correct solutions in a movement prediction task.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseCorrect extrapolation task solutions
    Study

    mousen: not reported in source

    C57BL/6J mice
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The ability of mice for extrapolation of the direction of stimulus movement differently changed after Noopept injections: the proportion of correct task solutions increased in C57BL/6J and BALB/c mice, whereas the performance of DBA/2J did not change.
    1 context sentence
    Summary · context
    The effect of nootropic drug Noopept (GVS-111, N-phenil-acetyl-L-prolylglycin ethyl ether) was shown to be genotype-dependent.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In BALB/c mice, noopept increased the proportion of correct stimulus-movement extrapolation task solutions.

    In plain wordsIn mice of the BALB/c strain, noopept increased correct solutions in a movement prediction task.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseCorrect extrapolation task solutions
    Study

    mousen: not reported in source

    BALB/c mice
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The ability of mice for extrapolation of the direction of stimulus movement differently changed after Noopept injections: the proportion of correct task solutions increased in C57BL/6J and BALB/c mice, whereas the performance of DBA/2J did not change.
    1 context sentence
    Summary · context
    The effect of nootropic drug Noopept (GVS-111, N-phenil-acetyl-L-prolylglycin ethyl ether) was shown to be genotype-dependent.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In DBA/2J mice, noopept did not change stimulus-movement extrapolation task performance.

    In plain wordsIn mice of the DBA/2J strain, noopept did not change movement prediction task performance.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeExtrapolation task performance
    Study

    mousen: not reported in source

    DBA/2J mice
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The ability of mice for extrapolation of the direction of stimulus movement differently changed after Noopept injections: the proportion of correct task solutions increased in C57BL/6J and BALB/c mice, whereas the performance of DBA/2J did not change.
    1 context sentence
    Summary · context
    The effect of nootropic drug Noopept (GVS-111, N-phenil-acetyl-L-prolylglycin ethyl ether) was shown to be genotype-dependent.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

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