In awake hamsters, acute melanotan II microinjections into the paraventricular nucleus increased interscapular brown adipose tissue temperature for as long as 4 h.
In plain wordsIn hamsters, melanotan II injected into a brain area called the PVH raised the temperature of brown fat for up to 4 hours.
- Peptide
- Melanotan II
- Outcome
- IncreaseInterscapular brown adipose tissue temperature
- Study
Siberian hamstern: not reported in source
- Outcome group
- Energy expenditure and thermogenesis · Metabolic and weight
- Studied dose
- Dose not stated · microinjection into the hypothalamic paraventricular nucleusAs given in this study (Siberian hamster).
Source sentences
Acute parenchymal MTII microinjections into the PVH of awake, freely-moving hamsters, using doses below those able to increase IBAT temperature when injected into the third ventricle, increased IBAT temperature for as long as 4 h, as measured by temperature transponders implanted below the tissue.