Skip to content

Study · Randomized controlled trial · n = 564 · 2009

4 results

Cetrorelix protocol versus gonadotropin-releasing hormone analog suppression long protocol for superovulation in intracytoplasmic sperm injection patients older than 40.

Sbracia M, Colabianchi J, Giallonardo A, Giannini P, Piscitelli C, Morgia F, Montigiani M, Schimberni M

Fertility and sterility23 May 2008Cited by 21 (Europe PMC)

PMID18501900 (opens in a new tab)DOI10.1016/j.fertnstert.2008.02.165 (opens in a new tab)PepBankPUB-18501900
Publisher pagePubMedAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women aged 40 or older undergoing IVF, cetrorelix yielded significantly fewer oocytes than the long protocol.

    In plain wordsIn women aged 40 or older undergoing IVF, cetrorelix yielded fewer eggs than the long protocol.

    Peptide
    Cetrorelix
    Outcome
    DecreaseOocytes retrieved
    Study

    n = 564

    Comparator
    Long protocol with GnRH analog suppression
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Patients treated with the long protocol showed a significantly higher number of oocytes retrieved and a higher pregnancy rate for both the cycle and transfer with respect to the cetrorelix protocol patients.
    2 context sentences
    Summary · context
    Five hundred sixty-four women 40 years or older undergoing IVF.
    Summary · context
    At their first IVF cycle, the women were randomized into two study groups using a computer-generated number sequence: 281 cases were treated with the cetrorelix protocol, and 283 patients were treated with a long protocol for controlled ovarian hyperstimulation.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women aged 40 or older undergoing IVF, pregnancy per cycle was significantly lower with cetrorelix than the long protocol.

    In plain wordsIn women aged 40 or older undergoing IVF, pregnancy per cycle was lower with cetrorelix than the long protocol.

    Peptide
    Cetrorelix
    Outcome
    DecreasePregnancy rate per cycle
    Study

    n = 564

    Comparator
    Long protocol with GnRH analog suppression
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Patients treated with the long protocol showed a significantly higher number of oocytes retrieved and a higher pregnancy rate for both the cycle and transfer with respect to the cetrorelix protocol patients.
    2 context sentences
    Summary · context
    Five hundred sixty-four women 40 years or older undergoing IVF.
    Summary · context
    At their first IVF cycle, the women were randomized into two study groups using a computer-generated number sequence: 281 cases were treated with the cetrorelix protocol, and 283 patients were treated with a long protocol for controlled ovarian hyperstimulation.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women aged 40 or older undergoing IVF, days of stimulation, estradiol on hCG day, FSH amount, embryos obtained and implantation rate did not differ significantly between cetrorelix and the long protocol.

    In plain wordsIn IVF patients aged 40 or older, stimulation days, estradiol, FSH amount, embryo number, and implantation did not differ significantly between cetrorelix and long protocols.

    Peptide
    Cetrorelix
    Outcome
    No significant changeDays of stimulation, estradiol on hCG day, FSH amount, embryos obtained, implantation rate
    Study

    n = 564

    Comparator
    Long protocol with GnRH analog suppression
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The other parameter evaluated did not show any statistically significant differences.
    3 context sentences
    Summary · context
    Days of stimulation, E(2) on the day of hCG administration, amount of FSH administered, number of oocytes yielded, number of embryos obtained, pregnancy rate, and implantation rate.
    Summary · context
    Five hundred sixty-four women 40 years or older undergoing IVF.
    Summary · context
    At their first IVF cycle, the women were randomized into two study groups using a computer-generated number sequence: 281 cases were treated with the cetrorelix protocol, and 283 patients were treated with a long protocol for controlled ovarian hyperstimulation.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In women aged 40 or older undergoing IVF, pregnancy per transfer was significantly lower with cetrorelix than the long protocol.

    In plain wordsIn women aged 40 or older undergoing IVF, pregnancy per transfer was lower with cetrorelix than the long protocol.

    Peptide
    Cetrorelix
    Outcome
    DecreasePregnancy rate per transfer
    Study

    n: not reported in source

    Comparator
    Long protocol with GnRH analog suppression
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Patients treated with the long protocol showed a significantly higher number of oocytes retrieved and a higher pregnancy rate for both the cycle and transfer with respect to the cetrorelix protocol patients.
    2 context sentences
    Summary · context
    Five hundred sixty-four women 40 years or older undergoing IVF.
    Summary · context
    At their first IVF cycle, the women were randomized into two study groups using a computer-generated number sequence: 281 cases were treated with the cetrorelix protocol, and 283 patients were treated with a long protocol for controlled ovarian hyperstimulation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.