In patients with severe COPD, expression of mechano growth factor in intercostal muscle was higher than in control subjects.
In plain wordsIn people with severe COPD, the body's own MGF levels in chest muscle were higher than in healthy people.
- Peptide
- MGF / PEG-MGF
- Outcome
- IncreaseMGF expression in intercostal muscle
- Study
n = 15
- Comparator
- Healthy control subjects
- Outcome group
- Muscle injury and repair · Respiratory
Measurements
- MGF expression
- 0.45 AU
- COPD patients
- MGF expression
- 0.13 AU
- control subjects
Source sentences
mechano growth factor, 0.45 (0.55) vs 0.13 (0.17) AU (P=.05).
1 context sentence(design, population, supporting numbers)
The study included 8 patients with severe COPD (mean [SD] forced expiratory volume in 1 second, 33% [9%] of predicted) and 7 control subjects in whom biopsies were performed of the external intercostal muscle.
This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.