In skin biopsies, mRNA of the body's own LL‑37 was not significantly higher in atopic dermatitis or psoriasis vulgaris patients than in controls, unlike the other antimicrobial peptides measured.
In plain wordsSkin of people with eczema or psoriasis did not have more of the body's own LL‑37 messenger RNA than healthy skin.
- Peptide
- LL-37
- Outcome
- No significant changeLL-37 mRNA in skin, atopic dermatitis and psoriasis versus controls
- Study
n = 95
- Comparator
- Healthy controls
- Outcome group
- Skin and hair · Skin and wound
Source sentences
Except for LL-37, mRNA of hBDs, psoriasin, and RNase 7 was significantly higher expressed in AD (n = 42) and/or PV (n = 35) patients when compared to controls (n = 18).
1 context sentence(design, population, supporting numbers)
Skin biopsies were obtained from healthy subjects and patients with AD and PV.
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.