In patients with ACTH-dependent Cushing's syndrome, tumoral GHSR-1a expression was higher in patients who responded to GHRP‑6 in vivo.
In plain wordsIn people with ACTH-dependent Cushing's syndrome, tumours had more GHSR-1a receptor in patients who responded to GHRP‑6.
- Peptide
- GHRP-6
- Outcome
- IncreaseGHSR-1a mRNA expression in patients with and without response to GHRP-6
- Study
n = 17
- Comparator
- Patients without in vivo response to GHRP-6
- Outcome group
- Receptor activity and mechanism · Endocrine and hormones
Source sentences
GHSR-1a expression was higher in patients (CD and EAS) presenting in vivo response to GHRP-6.
1 context sentence(design, population, supporting numbers)
Fifteen CD patients and two ectopic ACTH syndrome (EAS) patients were studied.
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.