In vitro, MRSA strains resistant to LL‑37 had significantly higher zeta potentials than MRSA strains susceptible to LL‑37.
In plain wordsIn lab tests, MRSA strains that resisted LL‑37 had a higher surface charge than strains that LL‑37 could kill.
- Peptide
- LL-37
- Outcome
- IncreaseZeta potential of LL-37-resistant versus susceptible MRSA
- Study
Staphylococcus aureusn: not reported in source
clinical MRSA and MSSA isolates- Comparator
- LL-37-susceptible MRSA strains
- Outcome group
- Infection and antimicrobial activity · Infection
- Studied dose
- Dose not stated
Source sentences
Of the 54 randomly selected S. aureus strains, those MRSA strains resistant to LL-37 showed significantly higher zeta potentials than those susceptible to LL-37 (P < 0.05).
1 context sentence(design, population, supporting numbers)
We examined the susceptibility of 190 clinical strains of methicillin-susceptible S. aureus (MSSA) and 304 strains of MRSA to two different classes of cationic antimicrobial peptides: LL-37 and human beta-defensin-3 (hBD3).