Effects of bioactive tetrapeptides on free-radical processes.

Kozina LS

Bulletin of experimental biology and medicine1 Jun 2007Cited by 2 (Europe PMC)

PMID18239817DOI10.1007/s10517-007-0230-8PepBankPUB-18239817

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study8

3 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In rats, injections of epithalon (with cortagen) decreased the content of LPO products.
In plain wordsIn rats, injections of epithalon (given with cortagen) lowered the level of lipid peroxidation products.
Peptide
Epitalon
Outcome
DecreaseLipid peroxidation (LPO) products
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Aging and longevity
Studied dose
Dose not stated
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products
Report a problemFND-1823981701
02AnimalAnimal study (in vivo)Efficacy outcome
In rats, injections of epithalon (with cortagen) reduced oxidative modification of proteins.
In plain wordsIn rats, injections of epithalon (given with cortagen) reduced oxidative damage to proteins.
Peptide
Epitalon
Outcome
DecreaseOxidative modification of proteins
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Aging and longevity
Studied dose
Dose not stated
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
Report a problemFND-1823981702
03AnimalAnimal study (in vivo)Efficacy outcome
In rats, injections of epithalon (with cortagen) were paralleled by suppression of antioxidant activity in serum and cerebral cortex.
In plain wordsIn rats, injections of epithalon (given with cortagen) went with lower antioxidant activity in serum and brain cortex.
Peptide
Epitalon
Outcome
DecreaseAntioxidant activity in serum and cerebral cortex
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Aging and longevity
Studied dose
Dose not stated
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
Report a problemFND-1823981703

Studies that did not test the peptide alone5

In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cortagen (AEDP).

04AnimalNot a test of Cortagen (AEDP) aloneAnimal study (in vivo)Mechanism
In rats, injections of epithalon and cortagen decreased serum lipid peroxidation products.
In plain wordsIn rats, epithalon and cortagen injections decreased serum lipid peroxidation products.
Peptide
Cortagen (AEDP)
Outcome
DecreaseSerum lipid peroxidation products
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Whole body
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortagen (AEDP).
Report a problemFND-1823981704
05AnimalNot a test of Cortagen (AEDP) aloneAnimal study (in vivo)Mechanism
In rats, injections of epithalon and cortagen decreased cerebral cortex lipid peroxidation products.
In plain wordsIn rats, epithalon and cortagen injections decreased cerebral cortex lipid peroxidation products.
Peptide
Cortagen (AEDP)
Outcome
DecreaseCerebral cortex lipid peroxidation products
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Nervous system and cognition
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortagen (AEDP).
Report a problemFND-1823981705
06AnimalNot a test of Cortagen (AEDP) aloneAnimal study (in vivo)Mechanism
In rats, injections of epithalon and cortagen reduced oxidative modification of proteins. The abstract did not identify the tissue.
In plain wordsIn rats, epithalon and cortagen reduced oxidative protein modification. The abstract did not identify the tissue.
Peptide
Cortagen (AEDP)
Outcome
DecreaseOxidative protein modification
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Whole body
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortagen (AEDP).
Report a problemFND-1823981706
07AnimalNot a test of Cortagen (AEDP) aloneAnimal study (in vivo)Mechanism
In rats, injections of epithalon and cortagen suppressed serum antioxidant activity.
In plain wordsIn rats, epithalon and cortagen injections suppressed serum antioxidant activity.
Peptide
Cortagen (AEDP)
Outcome
DecreaseSerum antioxidant activity
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Whole body
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortagen (AEDP).
Report a problemFND-1823981707
08AnimalNot a test of Cortagen (AEDP) aloneAnimal study (in vivo)Mechanism
In rats, injections of epithalon and cortagen suppressed cerebral cortex antioxidant activity.
In plain wordsIn rats, epithalon and cortagen injections suppressed cerebral cortex antioxidant activity.
Peptide
Cortagen (AEDP)
Outcome
DecreaseCerebral cortex antioxidant activity
Study
ratn: not reported in source
Rat serum and cerebral cortex
Outcome group
Oxidative stress · Nervous system and cognition
Source sentences
Summary
Injections of epithalon and cortagen to rats decreased the content of LPO products and reduced oxidative modification of proteins, which was paralleled by suppression of antioxidant activity in rat serum and cerebral cortex.
In this study, Cortagen (AEDP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortagen (AEDP).
Report a problemFND-1823981708

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Versions 4 to 10Current
28 Oct 2026, 02:02 UTC
The same notice was added 7 times, first on 21 Oct 2026, 17:05 UTC. The status did not change between them.
Study results updated
Version 3
21 Oct 2026, 16:35 UTC
Study data updated · source update from Europe PMC
Version 2
9 Oct 2026, 18:17 UTC
Study results updated
Version 1
9 Oct 2026, 02:47 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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