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Study · Measured the body's own peptide · 2008

2 results

Effects of eccentric cycling exercise on IGF-I splice variant expression in the muscles of young and elderly people.

Hameed M, Toft AD, Pedersen BK, Harridge SD, Goldspink G

Scandinavian journal of medicine & science in sports7 Dec 2007Cited by 19 (Europe PMC)

PMID18067523 (opens in a new tab)DOI10.1111/j.1600-0838.2007.00714.x (opens in a new tab)PepBankPUB-18067523
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialOther

    In young and elderly people, quadriceps MGF mRNA rose significantly after 1 h of eccentric cycling exercise in both age groups.

    In plain wordsIn young and older people, the body's own MGF mRNA in thigh muscle rose after eccentric cycling exercise.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA after eccentric cycling exercise
    Study

    n = 17

    Comparator
    Pre-exercise baseline
    Outcome group
    Growth hormone and IGF-1 · Musculoskeletal

    Source sentences

    Summary
    Eccentric cycling exercise resulted in a significant increase in the mean MGF mRNA in both young and old subjects but did not alter IGF-IEa mRNA levels in either age group.
    2 context sentences
    Summary · context
    IGF-IEa and mechano growth factor (MGF) were studied in response to 1 h of eccentric cycling exercise in young and old individuals.
    Summary · context
    Subjects (nine young, aged 20-27 years and eight elderly, aged 67-75 years) completed an eccentric exercise protocol that consisted of 60 min of reverse pedal cycling.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialOther

    At baseline, quadriceps MGF mRNA levels did not differ between young and elderly subjects.

    In plain wordsBefore exercise, the body's own MGF mRNA in thigh muscle was similar in young and older people.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeBaseline MGF mRNA level, young versus elderly
    Study

    n = 17

    Comparator
    Young versus elderly subjects
    Outcome group
    Growth hormone and IGF-1 · Musculoskeletal

    Source sentences

    Summary
    No difference was observed between the baseline levels of the two splice variants between the two subject groups.
    2 context sentences
    Summary · context
    IGF-IEa and mechano growth factor (MGF) were studied in response to 1 h of eccentric cycling exercise in young and old individuals.
    Summary · context
    Subjects (nine young, aged 20-27 years and eight elderly, aged 67-75 years) completed an eccentric exercise protocol that consisted of 60 min of reverse pedal cycling.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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