In an animal model of ghrelin-induced feeding, very low doses of intracerebroventricular melanotan II reduced ghrelin-dependent hyperphagia.
In plain wordsIn an animal study, very low doses of melanotan II given into the brain reduced the extra eating caused by ghrelin.
- Peptide
- Melanotan II
- Outcome
- DecreaseGhrelin-dependent hyperphagia
- Study
n: not reported in source
- Outcome group
- Appetite and food intake · Metabolic and weight
- Studied dose
- Dose not stated · intracerebroventricularAs given in this study.
Source sentences
very low doses of alpha-MSH and MTII administered ICV significantly reduced ghrelin-dependent hyperphagia.
1 context sentence(design, population, supporting numbers)
We found that very low doses of alpha-MSH and MTII administered ICV significantly reduced ghrelin-dependent hyperphagia.