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Study · Not a test of the peptide alone · 2007

3 results

Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.

Veldhuis JD, Keenan DM, Bowers CY

American journal of physiology. Regulatory, integrative and comparative physiology8 Aug 2007Cited by 5 (Europe PMC)

PMID17686882 (opens in a new tab)DOI10.1152/ajpregu.00438.2007 (opens in a new tab)PepBankPUB-17686882
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 01HumanNot a test of GHRP-2 aloneRandomized controlled trialMechanism

    In healthy women, the ER-alpha blocker fulvestrant lengthened GH secretory bursts stimulated by GHRH plus GHRP‑2.

    In plain wordsIn healthy women, an estrogen receptor blocker lengthened the GH bursts caused by a GHRH and GHRP‑2 combination.

    Peptide
    GHRP-2
    Outcome
    IncreaseDuration of GHRH/GHRP-2-stimulated GH secretory bursts with fulvestrant
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    fulvestrant extends GHRH/GHRP-2-stimulated secretory bursts
    2 context sentences
    Title · context
    Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.
    Summary · context
    stimulation of fasting GH secretion by pairs of GHRH, GHRP-2 (a ghrelin analog), and l-arginine (to putatively limit somatostatin outflow)

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 02HumanNot a test of GHRP-2 aloneRandomized controlled trialMechanism

    In healthy women, l-arginine plus GHRP‑2 lengthened GH secretory bursts whether or not estradiol was present.

    In plain wordsIn healthy women, an l-arginine and GHRP‑2 combination lengthened GH bursts with or without added estradiol.

    Peptide
    GHRP-2
    Outcome
    IncreaseDuration of l-arginine/GHRP-2-stimulated GH secretory bursts
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    l-arginine/GHRP-2 stimulation lengthens GH secretory bursts whether or not E(2) is present
    2 context sentences
    Title · context
    Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.
    Summary · context
    stimulation of fasting GH secretion by pairs of GHRH, GHRP-2 (a ghrelin analog), and l-arginine (to putatively limit somatostatin outflow)

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  3. 03HumanNot a test of GHRP-2 aloneRandomized controlled trialMechanism

    In healthy women, estradiol limited the ability of l-arginine plus GHRP‑2 to expand GH secretory bursts, and fulvestrant did not block this effect.

    In plain wordsIn healthy women, estradiol reduced how much an l-arginine and GHRP‑2 combination widened GH bursts, and the receptor blocker did not stop this.

    Peptide
    GHRP-2
    Outcome
    DecreaseEstradiol effect on l-arginine/GHRP-2 expansion of GH bursts
    Study

    n: not reported in source

    Comparator
    No estradiol
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    E(2) limits the capability of l-arginine/GHRP-2 to expand GH secretory bursts, and fulvestrant does not inhibit this effect
    2 context sentences
    Title · context
    Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women.
    Summary · context
    stimulation of fasting GH secretion by pairs of GHRH, GHRP-2 (a ghrelin analog), and l-arginine (to putatively limit somatostatin outflow)

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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