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Study · Not a test of the peptide alone · 2007

3 results

In vitro release study of mono-PEGylated growth hormone-releasing peptide-6 from PLGA microspheres.

Park EJ, Na DH, Lee KC

International journal of pharmaceutics14 Jun 2007Cited by 14 (Europe PMC)

PMID17644286 (opens in a new tab)DOI10.1016/j.ijpharm.2007.06.005 (opens in a new tab)PepBankPUB-17644286
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In vitro, mono-PEG-GHRP‑6 microspheres showed a lower initial burst than native GHRP‑6 microspheres.

    In plain wordsIn lab tests, mono-PEG-GHRP‑6 microspheres released less peptide initially than native GHRP‑6 microspheres.

    Peptide
    GHRP-6
    Outcome
    DecreaseInitial burst release
    Study

    n: not reported in source

    Comparator
    Native GHRP-6 microspheres
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    The mono-PEG-GHRP-6 microspheres showed a lower initial burst compared with native GHRP-6 microspheres and zero-order release profile for a 1-month period.
    1 context sentence
    Summary · context
    The microspheres encapsulating native GHRP-6 or mono-PEG-GHRP-6 were prepared using the single oil-in-water emulsion solvent evaporation method.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In vitro, mono-PEG-GHRP‑6 microspheres showed a zero-order release profile for a one-month period.

    In plain wordsIn lab tests, mono-PEG-GHRP‑6 microspheres showed a constant release rate for one month.

    Peptide
    GHRP-6
    Outcome
    Not applicableZero-order release profile
    Study

    n: not reported in source

    Outcome group
    Formulation, delivery and stability · Pharmacology

    Measurements

    Release period
    1 month
    mono-PEG-GHRP-6 microspheres

    Source sentences

    Summary
    The mono-PEG-GHRP-6 microspheres showed a lower initial burst compared with native GHRP-6 microspheres and zero-order release profile for a 1-month period.
    1 context sentence
    Summary · context
    The microspheres encapsulating native GHRP-6 or mono-PEG-GHRP-6 were prepared using the single oil-in-water emulsion solvent evaporation method.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03LabNot a test of GHRP-6 aloneIn vitro (cell-free)Other

    In vitro, smaller PEG attached to GHRP‑6 was associated with more rapid release than larger PEG.

    In plain wordsIn lab tests, GHRP‑6 with smaller attached PEG released faster than GHRP‑6 with larger attached PEG.

    Peptide
    GHRP-6
    Outcome
    IncreaseRelease rate by PEG size
    Study

    n: not reported in source

    Comparator
    Larger attached PEG size
    Outcome group
    Formulation, delivery and stability · Pharmacology

    Source sentences

    Summary
    The release period was dependent on the PEG size attached to the GHRP-6 with more rapid drug release being observed with the smaller PEG size.
    1 context sentence
    Summary · context
    The microspheres encapsulating native GHRP-6 or mono-PEG-GHRP-6 were prepared using the single oil-in-water emulsion solvent evaporation method.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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