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Study · Not a test of the peptide alone · 2007

3 results

Both orexin receptors are expressed in rat ovaries and fluctuate with the estrous cycle: effects of orexin receptor antagonists on gonadotropins and ovulation.

Silveyra P, Lux-Lantos V, Libertun C

American journal of physiology. Endocrinology and metabolism17 Jul 2007Cited by 68 (Europe PMC)

PMID17638707 (opens in a new tab)DOI10.1152/ajpendo.00179.2007 (opens in a new tab)PepBankPUB-17638707
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Cetrorelix was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cetrorelix.

  1. 01AnimalNot a test of Cetrorelix aloneAnimal study (in vivo)Mechanism

    In rats, cetrorelix prevented the increase in ovarian OX(1) expression.

    In plain wordsIn rats, cetrorelix prevented the rise in ovarian OX(1) expression.

    Peptide
    Cetrorelix
    Outcome
    DecreaseOvarian OX(1) expression
    Study

    ratn: not reported in source

    Cycling Sprague-Dawley rats
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Cetrorelix or Nembutal prevented the increases of OX(1) and OX(2) while blunting gonadotropin peaks.
    2 context sentences
    Summary · context
    PPO, OX(1), and OX(2) were determined by quantitative real-time RT-PCR in ovaries of cycling Sprague-Dawley rats on all days of the cycle.
    Summary · context
    Ovarian OX(1) and OX(2) expression was then studied after ovulation blockade with Cetrorelix or Nembutal.

    In this study, Cetrorelix was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cetrorelix.

  2. 02AnimalNot a test of Cetrorelix aloneAnimal study (in vivo)Mechanism

    In rats, cetrorelix prevented the increase in ovarian OX(2) expression.

    In plain wordsIn rats, cetrorelix prevented the rise in ovarian OX(2) expression.

    Peptide
    Cetrorelix
    Outcome
    DecreaseOvarian OX(2) expression
    Study

    ratn: not reported in source

    Cycling Sprague-Dawley rats
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Cetrorelix or Nembutal prevented the increases of OX(1) and OX(2) while blunting gonadotropin peaks.
    2 context sentences
    Summary · context
    PPO, OX(1), and OX(2) were determined by quantitative real-time RT-PCR in ovaries of cycling Sprague-Dawley rats on all days of the cycle.
    Summary · context
    Ovarian OX(1) and OX(2) expression was then studied after ovulation blockade with Cetrorelix or Nembutal.

    In this study, Cetrorelix was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cetrorelix.

  3. 03AnimalNot a test of Cetrorelix aloneAnimal study (in vivo)Mechanism

    In rats, cetrorelix blunted gonadotropin peaks.

    In plain wordsIn rats, cetrorelix reduced gonadotropin peaks.

    Peptide
    Cetrorelix
    Outcome
    DecreaseGonadotropin peaks
    Study

    ratn: not reported in source

    Cycling Sprague-Dawley rats
    Outcome group
    Receptor activity and mechanism · Reproductive and sexual health

    Source sentences

    Summary
    Cetrorelix or Nembutal prevented the increases of OX(1) and OX(2) while blunting gonadotropin peaks.
    2 context sentences
    Summary · context
    PPO, OX(1), and OX(2) were determined by quantitative real-time RT-PCR in ovaries of cycling Sprague-Dawley rats on all days of the cycle.
    Summary · context
    Ovarian OX(1) and OX(2) expression was then studied after ovulation blockade with Cetrorelix or Nembutal.

    In this study, Cetrorelix was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cetrorelix.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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