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Study · Animal study (in vivo) · 2006

3 results

Neuroprotective and antiamnesic effects of Semax during experimental ischemic infarction of the cerebral cortex.

Romanova GA, Silachev DN, Shakova FM, Kvashennikova YN, Viktorov IV, Shram SI, Myasoedov NF

Bulletin of experimental biology and medicine1 Dec 2006Cited by 10 (Europe PMC)

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In animals with focal photoinduced ischemia of the prefrontal cortex, intranasal Semax for 6 days decreased the volume of cortical infarction.

    In plain wordsIn animals with experimental stroke, Semax given through the nose for 6 days reduced the size of the brain damage.

    Peptide
    Semax
    Outcome
    DecreaseVolume of cortical infarction
    Study

    n: not reported in source

    Focal photoinduced ischemia of the prefrontal cortex
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intranasal · 6 daysAs given in this study.

    Source sentences

    Summary
    Intranasal administration of Semax for 6 days decreased the volume of cortical infarction and improved retention and performance of conditioned passive avoidance response.
    1 context sentence
    Summary · context
    Semax had a pronounced neuroprotective and antiamnesic effect during focal photoinduced ischemia of the prefrontal cortex.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In animals with focal photoinduced ischemia of the prefrontal cortex, intranasal Semax for 6 days improved retention of the conditioned passive avoidance response.

    In plain wordsIn animals with experimental stroke, Semax given through the nose for 6 days improved memory of a learned avoidance task.

    Peptide
    Semax
    Outcome
    IncreaseRetention of conditioned passive avoidance response
    Study

    n: not reported in source

    Focal photoinduced ischemia of the prefrontal cortex
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasal · 6 daysAs given in this study.

    Source sentences

    Summary
    Intranasal administration of Semax for 6 days decreased the volume of cortical infarction and improved retention and performance of conditioned passive avoidance response.
    1 context sentence
    Summary · context
    Semax had a pronounced neuroprotective and antiamnesic effect during focal photoinduced ischemia of the prefrontal cortex.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In animals with focal photoinduced ischemia of the prefrontal cortex, intranasal Semax for 6 days improved performance of the conditioned passive avoidance response.

    In plain wordsIn animals with experimental stroke, Semax given through the nose for 6 days improved performance in a learned avoidance task.

    Peptide
    Semax
    Outcome
    IncreasePerformance of conditioned passive avoidance response
    Study

    n: not reported in source

    Focal photoinduced ischemia of the prefrontal cortex
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasal · 6 daysAs given in this study.

    Source sentences

    Summary
    Intranasal administration of Semax for 6 days decreased the volume of cortical infarction and improved retention and performance of conditioned passive avoidance response.
    1 context sentence
    Summary · context
    Semax had a pronounced neuroprotective and antiamnesic effect during focal photoinduced ischemia of the prefrontal cortex.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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