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Study · Measured the body's own peptide · 2007

1 result

Therapeutic ultrasound decreases mechano-growth factor messenger ribonucleic acid expression after muscle contusion injury.

McBrier NM, Lekan JM, Druhan LJ, Devor ST, Merrick MA

Archives of physical medicine and rehabilitation1 Jul 2007Cited by 19 (Europe PMC)

PMID17601477 (opens in a new tab)DOI10.1016/j.apmr.2007.04.005 (opens in a new tab)PepBankPUB-17601477
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats with gastrocnemius contusion injury, nonthermal ultrasound decreased MGF mRNA expression in the treated limb compared with the untreated limb.

    In plain wordsIn rats with muscle bruising, ultrasound lowered the body's own MGF levels in the treated leg compared with the untreated leg.

    Peptide
    MGF / PEG-MGF
    Outcome
    DecreaseMGF mRNA after muscle contusion
    Study

    ratn = 32

    Wistar rats with gastrocnemius contusion injury
    Comparator
    Non-ultrasound contralateral hindlimb
    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Ultrasound treatments decreased MGF mRNA expression in the treated limb compared with the nontreated hindlimb (F(1,28)=6.605, P=.016, 1-beta=.699, eta(2)=.191).
    3 context sentences
    Summary · context
    Thirty-six 3- to 4-month-old male Wistar rats (mean weight, 280.8+/-21.5g).
    Summary · context
    Ultrasound treatment (frequency, 3MHz; intensity, 0.3W/cm(2); continuous duty cycle) was started 24 hours postinjury and delivered for 5 minutes daily on 4 consecutive days.
    Summary · context
    Treatment was on the left hindlimb and the contralateral right hindlimb was the nonultrasound control.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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