In Lewis lung carcinoma mice treated with IRX-2, adding Talpha1 significantly improved survival compared with IRX-2 alone.
In plain wordsIn mice with lung cancer, adding Talpha1 to IRX-2 improved survival compared with IRX-2 alone.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseSurvival of tumor-bearing mice
- Study
mousen: not reported in source
Lewis lung carcinoma tumor-bearing mice- Comparator
- IRX-2 alone
- Outcome group
- Tumor growth · Cancer
- Studied dose
- Dose not stated
Source sentences
adding Talpha1 led to significant improvement in survival of the tumor-bearing mice.
1 context sentence(design, population, supporting numbers)
We extended those studies with the Lewis lung carcinoma mouse model using IRX-2, a natural well-defined biologic containing multiple cytokines, in combination with Talpha1 (IRX-3).