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Study · Case report or series · n = 1 · 2007

2 results

In vivo response to growth hormone-releasing peptide-6 in adrenocorticotropin-dependent Cushing's syndrome by lung carcinoid tumor is associated with growth hormone secretagogue receptor type 1a mRNA expression.

Machado MC, Sá SV, Goldbaum TS, Catania M, Campos VC, Corrêa-Giannella ML, Giannella-Neto D, Salgado LR

Journal of endocrinological investigation1 Apr 2007Cited by 5 (Europe PMC)

PMID17556872 (opens in a new tab)DOI10.1007/bf03346301 (opens in a new tab)PepBankPUB-17556872
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanCase report or seriesActivity measurement

    In a man with ACTH-dependent Cushing's syndrome and lung carcinoid tumor, GHRP‑6 significantly increased ACTH.

    In plain wordsIn a man with Cushing's syndrome and a lung carcinoid tumor, GHRP‑6 increased ACTH.

    Peptide
    GHRP-6
    Outcome
    IncreaseACTH response
    Study

    n = 1

    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    He presented negative responses to human CRH and desmopressin tests; yet, a significant increase in ACTH after the GHRP-6 test was observed.
    1 context sentence
    Summary · context
    The patient was a 26-yr-old male with diagnosis of ACTH-dependent CS.

Studies that did not test the peptide alone1

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 02HumanNot a test of GHRP-6 aloneCase report or seriesMechanism

    In a man with lung carcinoid tumor, the ACTH response to GHRP‑6 was associated with tumor GHSR-1a expression.

    In plain wordsIn a man with lung carcinoid tumor, the ACTH response to GHRP‑6 was linked to receptor expression in the tumor.

    Peptide
    GHRP-6
    Outcome
    Not applicableAssociation of ACTH response with tumor GHSR-1a expression
    Study

    n = 1

    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    The ACTH response to GHRP-6 in a patient with ectopic ACTH production by a lung carcinoid tumor was associated with GHSR-1a expression in the tumor tissue, suggesting an association between GHSR-1a mRNA overexpression and the in vivo response to GHS.
    1 context sentence
    Summary · context
    The patient was a 26-yr-old male with diagnosis of ACTH-dependent CS.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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