In mouse spleen lymphocytes, a purified recombinant 4xTalpha1 concatemer protein (four tandem copies of the thymosin alpha‑1 gene product) stimulated cell proliferation in a preliminary MTT assay.
In plain wordsIn lab tests on mouse immune cells, a made-in-bacteria protein of four linked thymosin alpha‑1 copies made the cells multiply, in preliminary results.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseMouse spleen lymphocyte proliferation
- Study
mousen: not reported in source
spleen lymphocytes (MTT assay)- Outcome group
- Immune response · Immune and inflammation
Source sentences
Preliminary results showed that the 4xTalpha1 concatemer protein could stimulate the mice spleen lymphocyte proliferation.
1 context sentence(design, population, supporting numbers)
The expressed protein was purified and its bioactivity was analysed by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] assay.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.