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Study · Measured the body's own peptide · 2007

5 results

Identification of the neuropeptide content of individual rat neurohypophysial terminals.

Custer EE, Ortiz-Miranda S, Knott TK, Rawson R, Elvey C, Lee RH, Lemos JR

Journal of neuroscience methods14 Mar 2007Cited by 13 (Europe PMC)

PMID17452053 (opens in a new tab)DOI10.1016/j.jneumeth.2007.03.006 (opens in a new tab)PepBankPUB-17452053
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In isolated rat neurohypophysial terminals, the natural oxytocin content was lower than the vasopressin content.

    In plain wordsIn lab tests on rat nerve terminals, the body's own oxytocin content was lower than the vasopressin content.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin content of individual neurohypophysial terminals
    Study

    ratn: not reported in source

    Individual isolated neurohypophysial terminals
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    OT content
    1.77 pg
    individual neurohypophysial terminal, ELISA

    Source sentences

    Summary
    The NHT content of AVP (2.21+/-0.10 pg) was greater than OT (1.77+/-0.08 pg) and increased with terminal size.
    1 context sentence
    Summary · context
    The objective of this study was to develop a method that could reliably determine the arginine vasopressin (AVP) and/or oxytocin (OT) content of individual rat neurohypophysial terminals (NHT) >or=5 microm in diameter, the size used for electrophysiological recordings.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In isolated rat neurohypophysial terminals, oxytocin-positive terminals were smaller in diameter than vasopressin-positive terminals.

    In plain wordsIn lab tests on rat nerve terminals, terminals with natural oxytocin were smaller than those with vasopressin.

    Peptide
    Oxytocin
    Outcome
    Not applicableDiameter of oxytocin-positive terminals
    Study

    ratn: not reported in source

    Individual isolated neurohypophysial terminals
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    Diameter
    9.1 µm
    OT-positive terminals

    Source sentences

    Summary
    AVP-positive terminals (10.2+/-0.21 microm) were larger in diameter than OT-positive terminals (9.1+/-0.24 microm).
    1 context sentence
    Summary · context
    The objective of this study was to develop a method that could reliably determine the arginine vasopressin (AVP) and/or oxytocin (OT) content of individual rat neurohypophysial terminals (NHT) >or=5 microm in diameter, the size used for electrophysiological recordings.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In rat neurohypophysial terminals, a higher percentage of smaller terminals contained oxytocin and a higher percentage of larger terminals were colabeled.

    In plain wordsIn lab tests on rat nerve terminals, smaller terminals more often held natural oxytocin and larger terminals more often held both peptides.

    Peptide
    Oxytocin
    Outcome
    Not applicableProportion of oxytocin-containing terminals by cell type size
    Study

    ratn: not reported in source

    Individual isolated neurohypophysial terminals
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    Smaller terminals containing OT
    58%
    immunocytochemistry
    Larger terminals colabeled
    42%
    immunocytochemistry

    Source sentences

    Summary
    Immunocytochemical techniques indicated that a higher percentage (58%) of smaller terminals contained OT, and that a higher percentage (42%) of larger NHTs were colabeled.
    1 context sentence
    Summary · context
    The objective of this study was to develop a method that could reliably determine the arginine vasopressin (AVP) and/or oxytocin (OT) content of individual rat neurohypophysial terminals (NHT) >or=5 microm in diameter, the size used for electrophysiological recordings.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueOther

    In rat neurohypophysial terminals, immunocytochemistry found a higher percentage of oxytocin-positive terminals than ELISA.

    In plain wordsIn lab tests on rat nerve terminals, staining found more terminals with the body's own oxytocin than the ELISA test did.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-positive terminals by method
    Study

    ratn: not reported in source

    Individual isolated neurohypophysial terminals
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    OT-positive terminals
    43%
    immunocytochemistry
    OT-positive terminals
    26%
    ELISA

    Source sentences

    Summary
    there was a higher percentage of OT terminals when using immunocytochemistry (43%) compared to ELISA (26%).
    1 context sentence
    Summary · context
    The objective of this study was to develop a method that could reliably determine the arginine vasopressin (AVP) and/or oxytocin (OT) content of individual rat neurohypophysial terminals (NHT) >or=5 microm in diameter, the size used for electrophysiological recordings.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelEx vivo tissueOther

    In rat neurohypophysial terminals assayed for both vasopressin and oxytocin, the percentage of oxytocin-positive terminals decreased.

    In plain wordsIn lab tests on rat nerve terminals, fewer terminals counted as holding the body's own oxytocin when both peptides were tested together.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-positive terminals when assayed for both peptides
    Study

    ratn: not reported in source

    Individual isolated neurohypophysial terminals
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Measurements

    OT-positive terminals
    18%
    assayed for AVP and OT

    Source sentences

    Summary
    The percent of AVP-positive (60%) and OT-positive (18%) terminals decreased when NHT were assayed for both AVP and OT.
    1 context sentence
    Summary · context
    The objective of this study was to develop a method that could reliably determine the arginine vasopressin (AVP) and/or oxytocin (OT) content of individual rat neurohypophysial terminals (NHT) >or=5 microm in diameter, the size used for electrophysiological recordings.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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