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Study · In vitro (cell-free) · rat · 2006

1 result

Novel neuroprotective neurotrophic NAP analogs targeting metal toxicity and oxidative stress: potential candidates for the control of neurodegenerative diseases.

Zheng H, Blat D, Fridkin M

Journal of neural transmission. Supplementum1 Jan 2006Cited by 11 (Europe PMC)

PMID17447427 (opens in a new tab)DOI10.1007/978-3-211-33328-0_18 (opens in a new tab)PepBankPUB-17447427
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cell-free)Efficacy outcome

    In rat brain homogenates, NAP did not inhibit iron-induced lipid peroxidation even at 100 microM.

    In plain wordsIn lab tests with rat brain material, NAP did not inhibit iron-induced lipid damage even at 100 microM.

    Peptide
    Davunetide
    Outcome
    No significant changeIron-induced lipid peroxidation
    Study

    ratn: not reported in source

    Rat brain homogenates
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 microMAs given in this study (rat).

    Source sentences

    Summary
    M98 and M99 exhibited significant inhibition of iron-induced lipid peroxidation in rat brain homogenates at concentrations of > or = 30 microM, while NAP failed to show any inhibition even at 100 microM.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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