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Study · Measured the body's own peptide · 2007

4 results

Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humans.

Bamman MM, Petrella JK, Kim JS, Mayhew DL, Cross JM

Journal of applied physiology (Bethesda, Md. : 1985)29 Mar 2007Cited by 142 (Europe PMC)

PMID17395765 (opens in a new tab)DOI10.1152/japplphysiol.00024.2007 (opens in a new tab)PepBankPUB-17395765
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialMechanism

    In previously untrained adults, 16 weeks of progressive resistance training increased muscle MGF mRNA by the first loading bout (T2).

    In plain wordsIn untrained adults, resistance training raised the body's own MGF levels in muscle.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA after resistance training, entire cohort
    Study

    n = 66

    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    For the entire cohort, IGF-IEa, MGF, and myogenin mRNAs were upregulated by T2 (P<0.05), while MyoD did not increase significantly until T3 (P<0.001).
    1 context sentence
    Summary · context
    We applied K-means cluster analysis to test the hypothesis that muscle-specific factors known to modulate protein synthesis and satellite cell activity would be differentially expressed during progressive resistance training (PRT, 16 wk) in 66 human subjects experiencing extreme, modest, and failed…

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialMechanism

    In modest hypertrophy responders, MGF mRNA rose by 73% with resistance training.

    In plain wordsIn adults with modest muscle fibre growth, resistance training raised the body's own MGF by 73%.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA in modest responders
    Study

    n = 32

    Outcome group
    Muscle injury and repair · Musculoskeletal

    Measurements

    MGF mRNA increase
    73%
    Mod

    Source sentences

    Summary
    Within clusters, MGF and myogenin upregulation was robust in Xtr (126% and 65%) and Mod (73% and 41%) vs. no changes in Non.
    1 context sentence
    Summary · context
    We applied K-means cluster analysis to test the hypothesis that muscle-specific factors known to modulate protein synthesis and satellite cell activity would be differentially expressed during progressive resistance training (PRT, 16 wk) in 66 human subjects experiencing extreme, modest, and failed…

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelNon-randomized trialMechanism

    In extreme hypertrophy responders, MGF mRNA rose by 126% with resistance training.

    In plain wordsIn adults whose muscle fibres grew the most, resistance training raised the body's own MGF by 126%.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA in extreme responders
    Study

    n = 17

    Outcome group
    Muscle injury and repair · Musculoskeletal

    Measurements

    MGF mRNA increase
    126%
    Xtr

    Source sentences

    Summary
    Within clusters, MGF and myogenin upregulation was robust in Xtr (126% and 65%) and Mod (73% and 41%) vs. no changes in Non.
    1 context sentence
    Summary · context
    We applied K-means cluster analysis to test the hypothesis that muscle-specific factors known to modulate protein synthesis and satellite cell activity would be differentially expressed during progressive resistance training (PRT, 16 wk) in 66 human subjects experiencing extreme, modest, and failed…

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelNon-randomized trialMechanism

    In nonresponders with no myofiber hypertrophy, MGF mRNA did not change with resistance training.

    In plain wordsIn adults whose muscle fibres did not grow, resistance training did not change the body's own MGF.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF mRNA in nonresponders
    Study

    n = 17

    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    Within clusters, MGF and myogenin upregulation was robust in Xtr (126% and 65%) and Mod (73% and 41%) vs. no changes in Non.
    1 context sentence
    Summary · context
    We applied K-means cluster analysis to test the hypothesis that muscle-specific factors known to modulate protein synthesis and satellite cell activity would be differentially expressed during progressive resistance training (PRT, 16 wk) in 66 human subjects experiencing extreme, modest, and failed…

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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