In ad libitum fed mice, intraperitoneal GHRP‑6 did not alter circadian phase.
In plain wordsIn mice with free access to food, GHRP‑6 did not change the timing of the body clock.
- Peptide
- GHRP-6
- Outcome
- No significant changeCircadian phase of locomotor activity in ad libitum fed mice
- Study
mousen: not reported in source
mouse in vivo locomotor activity rhythm- Outcome group
- Circadian rhythm · Nervous system and cognition
- Studied dose
- Dose not stated · intraperitonealAs given in this study (mouse).
Source sentences
In vivo, intraperitoneal administration of ghrelin or a synthetic analog, growth hormone-releasing protein-6 (GHRP-6), to ad libitum fed animals failed to alter circadian phase.
1 context sentence(design, population, supporting numbers)
We examined the response of the SCN to ghrelin treatments in vitro, by means of electrophysiological and bioluminescence recordings, and in vivo, by assessing effects on the phase of locomotor activity rhythms.